OneChronos | Systems Engineers + Software Engineer, Data Platform | NYC (HQ), London or Amsterdam | Flexible / Remote | Full-Time

We offer a strong engineering culture and are looking for engineers to design and optimize high-performance trading systems that power our periodic auction matching infrastructure.

We build production systems in Rust and are seeking engineers with meaningful Rust, C++, Java, or Python experience, particularly from backend or systems-oriented environments.

Systems Engineer Systems programming role focused on low-latency, high-throughput distributed computing. Work across order and data workflows, auction execution, reliability, and performance optimization to ensure the platform is efficient, fault-tolerant, and capable of complex trade matching at scale.

We’re especially interested in engineers who: Have built backend or systems-level software Care deeply about performance, concurrency, and correctness Are motivated by real-time, performance-sensitive systems Have experience with compilers, static analysis, or language tooling (a strong plus)

Software Engineer, Data Platform Build and evolve the infrastructure behind our analytics platform. The role sits between data engineering and backend development and focuses on high-volume, time-sensitive data pipelines and workflow systems that process terabytes of trading data and billions of rows daily.

We’re especially interested in engineers who:

Have built internal data platforms or large-scale pipelines (Python/SQL; Rust a plus) Have experience with workflow orchestration (Temporal, Airflow, Dagster, etc.) Have worked with large datasets, columnar formats (Parquet/Arrow), and production data systems

CONTACT: careers@onechronos.com – please include “HN” in the subject line. ADDITIONAL OPENINGS: https://www.onechronos.com/careers/

Apple | SRE | San Diego | Full-time

You will work closely with developers who are building applications in Python and JavaScript, ensuring their code runs seamlessly in production. Your role will involve driving solutions for hybrid infrastructure (both on-premise and public cloud) and architecting our AWS-based platform. You will manage technologies such as Pulumi, Argo, Docker, Kubernetes, Postgres, and DataDog, combined with custom Apple software and tooling. You will oversee and enhance the CI/CD pipeline and support deployment of QA’s automated testing. You will monitor performance of the infrastructure and identify areas of improvement. You will identify infrastructure needs for new projects and coordinate with developers to ensure they are factored into the development process.

Apply here: https://jobs.apple.com/en-us/details/200648948/tools-and-pro...

MongoDB | Staff/Senior Security Software Engineer or SRE - Infrastructure Security | REMOTE (US) or HYBRID (NYC) | Full-Time

We are looking for experienced Software and Site Reliability Engineers to help secure the foundation of MongoDB Atlas, our globally distributed, multi-cloud database platform running across AWS, GCP and Azure.

This is a builder role, focusing on security tooling and observability, runtime detection, hardening policies, and infrastructure-as-code guardrails that protect our massive infrastructure.

Some of the things we're working on:

- Building secure-by-default infrastructure leveraging Linux, eBPF and Kubernetes security mechanisms, and implementing runtime detection and monitoring.

- Developing our in-house CSPM (Cloud Security Posture Management) and Vulnerability Management platforms.

- Integrating security directly into our CI/CD workflows and Terraform pipelines.

We're looking for engineers with a strong systems mindset who have some of:

- 5+ years of experience in SWE, SRE, or similar roles with some relevant security experience.

- Proficiency in one programming language: Golang, Rust, Python, C/C++ etc.

- Deep understanding of Linux internals, networking, and Kubernetes security.

- Familiarity with one major cloud provider (AWS, GCP or Azure.)

- A builder's mentality: you think about failure modes, observability, and operability alongside security and correctness.

For any questions, or to apply (mention HN): Email: hani.benhabiles+hn@mongodb.com JD: https://www.mongodb.com/careers/jobs/7727896

Other SRE / Infrastructure teams as are also hiring. Happy to help.

Shapes | Fullstack Engineer (AI Product) | ONSITE | San Francisco | Full-time

We’re building an AI chat platform where humans and AI interact in group chats, voice, and video.

Small team, high ownership, ship fast. We talk to users and build things we actually use.

We’re looking for a fullstack engineer to build product features end-to-end.

What you’ll do: - Build and ship features across frontend and backend - Work on real-time chat, onboarding flows, and AI interactions - Own features from idea → production - Collaborate closely with design and iterate quickly

Tech stack: React / Next.js, Python, real-time systems

Looking for: - Strong fullstack experience - Product mindset (you care about UX, not just code) - High agency - you move fast and take ownership

Apply: https://jobs.shapes.inc

SEEKING | AI/ML Engineer | Auburn AL → SF/Seattle/NYC/Remote | F-1 STEM OPT through Feb 2028 (no sponsorship needed)

4 yrs production GenAI: AWS Bedrock RAG (92% recall, HIPAA), LangGraph multi-agent copilots shipped to prod, QLoRA/LLaMA 2 fine-tuning, LangChain/LlamaIndex, Python, Docker/K8s.

Co-author ACL 2024 (healthcare AI). MS Data Science UNT 2024. Currently ML Research Scientist @ Auburn (multi-agent VLMs).

Open to: Applied Scientist / ML Eng / GenAI Eng / AI Eng

Email: ksaimanikanta4@gmail.com GitHub: github.com/saikasireddy Resume: [https://docs.google.com/document/d/1pjp-I0XfRP96fxu-nbIdOAVQ...]

Farmer Sam LLC | Multiple Roles | Remote | Equity/Founding Team

We build AI-powered agricultural tools through the Claude Partner Network. Team holds CCA certification. Looking for people who want founding equity in a small, remote-first company doing real work at the intersection of agtech and LLMs.

Roles: Full-Stack Engineer, ML/AI Engineer, Agricultural Data Scientist, Business Development

Stack: Claude API, Python, React, geospatial data pipelines.

https://www.farmersamllc.com | hello@farmersamllc.com

Deepline | NYC (ONSITE) | Founding Full-stack Engineers and Forward Deployed Engineers | $160k–$220k + meaningful equity

User interfaces are dead. Knowledge workers will exclusively work through agent interfaces like Claude Code/Cowork. We've built the interface layer to enable that.

One API that unifies hundreds of data providers, workflows, and data infrastructure to agents like Claude Code. We shipped our mvp last month; hundreds of early adopters signed up and are using Deepline.

You’d build core platform: agent-facing abstractions, infrastructure, UI. TypeScript/Python/Next.js/Postgres. $3.3M raised from Lerer Hippeau + Looker founding team. Technical founding team from Uber, Lyft, Capchase, MIT Lincoln Lab, Waterloo.

https://code.deepline.com/careers

HostGPO | Full-time | Remote | $200,000 - $240,000 / yr + equity

We’re looking for a Lead Engineer to help shape the future of HostGPO’s platform, data systems, and technical direction. This person will be a senior builder and technical leader - someone who can architect and ship scalable systems, navigate messy real-world business logic, and partner across the organization to solve problems.

- Strong full-stack fluency, with particular preference for Python, JavaScript/TypeScript, and React - Experience building and scaling backend systems, APIs, data platforms, and large-scale web applications - Experience with GraphQL and modern application architecture

Apply here on LinkedIn: https://lnkd.in/ezEQr_FX

Twindo (Formerly Canvas; The Spatial Computing Company) | Full-time | Remote

At Twindo, we’re working on spatial computing - using computer vision to 3D reconstruct and understand your surroundings so that software can operate over real-world spaces.

Twindo brings together everything that professionals need to understand the spaces they design, build, and manage, without extra site visits or second-guessing. With a quick scan or plan upload, any space becomes structured, accurate, design-ready data your whole team can actually use.

- Backend Engineer (Europe or LatAm Remote) - Full Stack Engineer (Europe or LatAm Remote) - iOS & Backend Engineer (Europe or LatAm Remote)

For detailed information check out https://www.twindo.com/careers/ or email jobs@twindo.com

Keywords: 3D, computer vision, photogrammetry, geomatics, SLAM, CAD, iOS, Python, Django

Carnegie Hall | C# Sitecore Developer | NYC, NY | Onsite | 105,000 USD /year | Full-Time

Come build the website for Carnegie Hall! It's a small team that works with the entire organization on all kinds of development projects. Mostly C# and a little python. Sitecore experience would be great but other CMS experience considered.

Apply here: https://jobs.dayforcehcm.com/en-US/carnegie/CANDIDATEPORTAL/...

Turquoise Health is a series C HealthTech startup, spread out remotely across the USA.

We are hiring for full time software engineers for our product engineering team to tackle the black hole of what is now America's healthcare revenue cycle. If you are a high performing full stack engineer who can be collaborative, innovative yet operates with no ego then we want you.

Our tech stack here is as follows: Python, Django, FastAPI, React, Typescript, Vue.Js etc

Engineering Manager, Data Products: https://jobs.ashbyhq.com/turquoise-health/e3b8b4e7-d1a7-4329...

Sr SWE, Consumer- https://jobs.ashbyhq.com/turquoise-health/f0c47e0e-ff1a-480c...

Sr Swe, Contracts-https://jobs.ashbyhq.com/turquoise-health/1d3ec150-1bf0-45df...

Cloud Data Engine (CDE) | Experienced Python Software Engineer | France | HYBRID

We’re hiring an experienced Python engineer to work on a platform for compliance monitoring and interoperable service catalogues.

You’d work on backend services, REST APIs, compliance pipelines, rule engines, JSON-LD/RDF, Verifiable Credentials, and regulatory-to-technical rule translation.

Stack: Python 3, FastAPI, async, RDF4J, Docker, GitLab CI/CD.

Looking for: 5+ years Python in production, strong API/data modelling/system design skills, fluent French, professional English.

Nice to have: RDF/SPARQL, Kubernetes, LLM pipelines.

Apply via Linkedin: https://www.linkedin.com/jobs/view/4399261912/?refId=hjnUg4M...

Arvo | Founding Engineer | NYC | Hybrid | Full-time

Arvo is building an AI meeting assistant for investment banking and private equity.

We’re hiring a Founding Engineer to work closely with the founders across desktop, backend, and AI workflows. It’s a high-ownership role with real influence on product, architecture, and execution.

Stack: Rust, React, Tauri, Python/FastAPI, SQLite, Postgres, LLMs, speech/transcription infrastructure

More here: https://arvohq.notion.site/Founding-Engineer-2e937d75c2a7805...

b.well | Sr SRE | US - Remote | bwell.com | Salary: $154-190,000 DOE

https://www.icanbwell.com/careers/?gnk=job&gni=8a78859e9cd55...

Company: We are the Healthtech powering brands like Google, Samsung, Perplexity, OpenAI, Noom and others. We are empowering people to own their health data and to drive detailed insights so they can make more informed decisions.

Stack: AWS, EKS (Bottlerocket), Alpine Imagges, Groundcover (Obersvability)

Job Description

As a Senior Site Reliability Engineer you will be tasked with making sure we build a reliable, secure and efficient platform for the b. Well network. You will be encouraged to blog, speak, and join events to talk about the work you are doing and encourage other companies to follow our lead. We will build solutions to delight our customers, employees and business. This role will also focus heavily on automation as it is a core value to our business from reliability to scaling.

What you will do:

-Let the robots do the work! We want you to focus on automating everything from building infrastructure, monitoring and disaster recovery

-Python, Rust, Go Go Go. Whatever you are comfortable in programming/scripting in we just want to see you deliver

-Love Penguins? We do too, whatever your flavor of Linux is bring your deep technical experience to the team

-New Platform, who dis? Build new solutions that enable our business and pass the knowledge on to your peers

-Like the Eye of Sauron you will monitor our infrastructure for anomalies and issues

-Code is for building solutions, not in how you communicate. Work well with your peers and communicate clearly so they understand the WHY behind what we do

-Must feed, water and provide high fidelity low friction platform solutions to engineers to keep them happy

-Write the ancient artifacts of documentation so your peers know how things work in the environment and write policies/procedures that make sense for the business

-Pass on your knowledge and wisdom to your other team members

-You like reading about the latest technology and trying it out? Come get paid for it!

Curie | AI Engineer | Hybrid (Chicago), Remote (San Francisco) | Full-time

Curie is a telehealth platform combining clinical expertise with AI to deliver personalized, accessible care — intelligent intake, treatment matching, and AI-powered tools for clinicians. Team includes ex-founders, clinicians, and engineers from Stanford, Harvard, UCLA, Berkeley, and AWS. Well-funded and growing fast.

We're hiring an AI Engineer to own the microservice layer powering our clinical AI: agentic intake workflows, RAG pipelines grounded in medical guidelines, session/memory management for long-running clinical agents, and HIPAA-grade observability and safety guardrails. You'll shape the AI architecture of a healthcare product from the ground up.

Stack: Langgraph, Langfuse, Go, Python, TS, GraphQL, gRPC/Connect-RPC, PostgreSQL, GCP/Vertex AI, AWS Bedrock.

Looking for: 5+ years engineering, meaningful production AI/ML experience, LLMs in production (prompting, structured output, evals), RAG and agentic patterns, comfort across Go + Python + cloud. Bonus: FHIR/HL7, fine-tuning, healthcare AI background, startup experience.

Apply: https://jobs.ashbyhq.com/curie/cea56a9a-d238-4101-a56c-f94a4...

Prosper AI | getprosper.ai | ONSITE Barcelona | Full-time

We build AI phone agents for US healthcare — insurance claims, benefit verification, scheduling. 300K+ calls/month, Series A closed, R&D fully in Barcelona.

Stack: Python, FastAPI, React/TypeScript. Small eng team, fast pace, real ownership.

Hiring for: - Senior Software Engineer: https://jobs.ashbyhq.com/prosper-ai/29fbeb7b-5673-498f-8333-... - Software Engineer: https://jobs.ashbyhq.com/prosper-ai/92f63920-a269-4039-8cf9-...

3–4 days onsite in Eixample. Stock options. ~2 week process.

Questions welcome, feel free to email our freelance recruiter Todora at hello@todora.co

Freight Brokerage | NJ | Founding Backend Architect (Python/PostgreSQL) | Remote (US, EST hours) | $150K + benefits

We're a freight brokerage in NJ building a self-hosted, AI-first platform to replace our legacy CRM/TMS.

The AI compute infrastructure and data foundation are already in place. We need the architect who turns it into a production operating system.

This is a systems architecture role, not a feature dev role. If your primary strength is writing features or following tickets, this is not the role.

You will be responsible for: designing and deploying a PostgreSQL schema for complex freight operations across 30+ entities. Building Python service layers integrating multiple REST APIs. Wiring locally-hosted LLM inference into business workflows. Structuring systems that involve document ingestion, email processing, and asynchronous event-driven pipelines. Defining backend patterns for reliability and maintainability across a multi-million record environment.

The entire stack is self-hosted on custom-built server hardware. Database, application layer, AI inference — all of it. No cloud dependencies. No API rate limits. No monthly GPU bills. No vendor lock-in. You have direct access to the metal, you deploy on your terms, and the only ceiling on what you can run is the hardware itself.

If you've ever wanted to build a production platform without a cloud provider standing between you and your infrastructure, this is that role.

You are the first technical hire. You report directly to the owner, who is directly involved in this hire and in daily collaboration on the build. Architectural decisions are yours to make. AI coding tools and low-code UI frameworks are part of the workflow — your time goes to data models, service orchestration, and API plumbing, not hand-building screens.

Stack: Python, PostgreSQL, FastAPI, Docker, Neo4j, Linux, vLLM. Preferred: freight/TMS domain, Microsoft Graph API, CRM migration experience.

1-week paid onsite onboarding in NJ, then fully remote. Equity conversation open once mutual fit is established.

To apply, send: (1) your resume, (2) a brief writeup of a system you designed end-to-end — not code, but the architecture decisions you made and why, (3) a short note on why this role interests you.

nj.technical.hire.spring.2026@proton.me

BillionToOne (YC S17, NASDAQ: BLLN) | Menlo Park, CA | Onsite

We're a molecular diagnostics company. YC made a video of us recently: https://www.youtube.com/watch?v=kkv5rZhrLkc.

Our software team creates products that help detect prenatal genetic conditions non-invasively and uncover 50%+ more cancer treatment options. Your code reaches patients and the providers making decisions for them.

Stack: Python, React, TypeScript, AWS, Postgres. We believe in small teams with high ownership.

We're hiring:

- Senior Software Engineer (Prenatal, Oncology, Digital Experiences)

- Senior AI Engineer

- AI Engineering Intern

- Lead UX Designer / Designer

See our engineering specific recruiting page at https://engineering.billiontoone.com/#roles. You can reach out to me directly with a resume at kwu@billiontoone.com.

BrandMultiplier | Head of AI & Engineering | REMOTE | Fractional-to-Full-Time | Equity

We're a profitable B2B services company ($3M–$50M ARR clients) actively building a proprietary AI platform — and we need the technical leader to own the execution.

WHAT WE'RE BUILDING: A multi-agent AI platform that operationalizes our founder-story methodology into deployable client systems. Architecture spec exists, pieces are already in production. We're not starting from scratch — we're scaling a real build.

THE STACK: LLMs (Claude, GPT, Gemini), multi-agent orchestration (LangGraph/LangChain), RAG pipelines, vector databases, React/Next.js, Python/Node.js, AWS, n8n/Make for automation.

WHAT MATTERS MOST: You're not just an executor. You come to the leadership table with tools and approaches we haven't seen yet. You translate the CEO's vision into a technical spec, a build plan, and a shipped product — without needing everything pre-defined.

THE TEAM: 4 core people. You'd join the CEO, a Growth Strategist, and an Operations Manager — and lead one AI Engineer (your first direct report).

ENGAGEMENT: Starts fractional with a clear path to full-time and equity for the right fit. We're not VC-funded by design, so equity is unencumbered.

Read the full spec here: https://www.notion.so/brandmultiplier/Head-of-AI-Engineering...

Full-Stack Engineer (Python / React) , Remote

We’re working on building production AI systems , not demos ,focused on real-world workflows, data pipelines, and integrating LLM-based systems into usable products.

Stack: - Python (FastAPI) - React / TypeScript - AWS / PostgreSQL

Work includes: - designing backend systems and APIs - building and scaling LLM workflows (agents, pipelines, RAG) - handling real-world issues like latency, reliability, and hallucination control - integrating AI into product experiences end-to-end

Looking for engineers who: - have built production systems (not just prototypes) - are strong on backend design and data flow - have experience with AI/LLM systems in real use cases

Remote, async-friendly, with some overlap with US timezones preferred.

If interested, apply here: https://lnkd.in/dbiCSZhW