Channable | Utrecht, Netherlands | HYBRID

Channable is a fast-growing B2B SaaS platform that offers a fully integrated way to market your products online. We empower marketers and online businesses to manage, scale, and optimise their marketing.

We're looking for a Python Software Engineer to join us! For more information, please check the job description: https://jobs.channable.com/o/python-software-engineer-pip

We use the following technologies and tools: Python (3.13), PostgreSQL, pydantic, sqlalchemy, typing, requests, logging, flask, fastapi, pytest, mypy, ruff, Sentry, Prometheus, Grafana, Loki

Do you want to read more about our engineering culture? Then have a look at our popular tech blog: https://tech.channable.com

Additionally, you can also take a look at some of our open-source work at https://github.com/channable to get a feeling of how we work together and what our code looks like.

Please note that candidates are required to be located or willing to relocate to the Netherlands. We work on a hybrid policy, and we go to our beautiful office in the city center of Utrecht twice per week.

Multiply | Python + SQL Software Engineer | On-site | Mauritius

We build repricing software that keeps online sellers on top of their competition on 130+ marketplaces.

Stack: Python, Postgres, FastAPI, SQLAlchemy.

Our office is beautifully located in Mauritius. We sponsor visas and handle all relocation/immigration.

Apply: jobs@multiply.cloud

Lantern | https://withlantern.com | Software Engineers (Python, Full-Stack) | Full time in New York, NY (ONSITE)

Lantern is building AI-powered revenue intelligence—think autonomous agents that turn cold outreach into warm conversations. Our platform automatically detects buying signals across your tech stack [1], prioritizes opportunities, and helps B2B sales teams focus on deals that actually close. We're an agentic-first startup building with Python, BAML, FastAPI, Next.js, and React, backed by a modern data stack (Postgres, ElasticSearch, ClickHouse, DuckDB). We deploy on Kubernetes/AWS and use Temporal.io for workflow orchestration. We're hiring software engineers who want to work on cutting-edge AI and agentic systems. You'll translate complex customer needs into scalable architecture, optimize AI model efficiency through prompt engineering, and ship features that directly impact how revenue teams operate. We value ownership, bold ideas, and people who want to push boundaries.

This role is based in our Manhattan office (4 days/week in-person). We offer full health and dental coverage. Apply here: https://forms.gle/kEi5MDDiaJKdyN3fA I'm Maksym. If you're excited about agentic AI and reshaping B2B sales, shoot me a note at maksym (at) withlantern.com.

Rapport | Founding AI Engineer + Founding Data Engineer | REMOTE (US) | Full-time | USD$160-220K+

Rapport is fixing healthcare's broken payment infrastructure. Hospitals lose billions annually to opaque payer rules and outdated contracts. We're an AI driven platform that ingests contracts, claims, and policies at scale, transforming them into real-time pricing intelligence to help get providers paid what they deserve.

We are backed by top tier investors and already have one of the largest RCM operators in the country as our development partner. Founded by a healthcare tech veteran with two prior exits. This is a chance to be a true founding team member with meaningful equity and direct impact on product and company direction.

Role 1: Founding AI Engineer – Claims Pricing Intelligence Build production pricing engines that transform messy healthcare data into accurate claim prices. Think of it like playing a complex game: interpret intricate payer rules, combine them into working logic, and validate at scale. Design data pipelines for PDFs/CSVs/APIs, create business logic combining rules based systems with ML validation, and build explainable systems where every decision is traceable. Thanks to our partnership, you'll work with massive real world datasets from day one. Stack: Python, SQL, FastAPI, LLMs and Agentic frameworks.

Role 2: Founding Data Engineer Architect our data platform from scratch. Build fault tolerant pipelines using Databricks that handle diverse sources, design normalization layers for healthcare data, and implement observability for production reliability. First data hire, you'll shape our entire data strategy. Stack: Python, SQL, Databricks, Azure/AWS, Airflow/Prefect.

Rapport is a remote only company with quarterly in person sessions. Significant equity + competitive compensation.

Apply: hiring@healthyrapport.com with resume or LinkedIn.

Please note we are unfortunately unable to sponsor visas or hire candidates outside of the US at this time.

Ezra | Principal Engineer (Full-Stack) | US REMOTE | Full-time

Ezra is a venture-backed startup building at the intersection of finance and artificial intelligence. We're building a platform to accelerate capital deployment into world-positive investments.

I'm Rob, the CTO, and we're looking for a technical leader and IC (12+ years exp) to own our backend architecture and implementation. You will be bridging traditional backend services with AI agents and inference systems, ensuring reliability at production scale. This is a high-autonomy role for someone who thrives in early-stage environments. You'll be working with other high performing engineers who will each own key components of our system.

The Role:

Drive architecture for Python-based backends (Django/FastAPI) and AI inference systems.

Build agentic AI workflows (retrieval strategies, eval sets) using OpenAI/Anthropic/LlamaIndex/Langchain.

Own features end-to-end, from system design to React/Next.js frontend implementation.

Stack: Python, Django/FastAPI, React, Next.js, AWS (RDS/Postgres, Terraform), Vector stores.

Contact: Email me directly at robert+hn25@ezra.fi with your resume, or apply here: https://www.ezra.fi/careers/principal-fullstack

Bidaya AI | Senior Software Engineer (Full Stack) | Calgary, Canada | HYBRID | Full-time | Up to $140k CAD + Generous Equity

We're an early-stage (pre-seed) VC-backed startup automating RFP proposals for the AEC (Architecture, Engineering, Construction) industry.

We are building an agentic AI platform that embeds directly into Microsoft Word, helping firms find and win more work, while serving as their knowledge management hub for all business development.

You would be the first full-time engineering hire working directly with the founders (I'm the technical co-founder). We need someone who can ship production code across the whole stack.

The Stack: - Frontend: Next.js, React - Backend: FastAPI (Python), Temporal

Hard problems you will solve:

Deep Word Integration: Building a high-performance, "Cursor-like" experience within the constraints of Office.js.

Agentic Workflows: Orchestrating AI agents that can read complex government requirements, reason about compliance, and generate winning output autonomously.

Evolving Knowledge Graph: Architecting a library system that doesn't just store files, but learns from project history and feedback loops.

If you want a chance to work on a hard problem, in an exciting space, with a strong team that has validated the market and de-risked the business, with major upside, let's talk!

To apply, email me directly: majd [at] bidaya.ai or [here](https://app.dover.com/apply/bidaya/d5f29bbb-9c67-4c4e-82bf-5...) Mention HN in the subject.

Kernel Intelligence | Senior Backend Systems Engineer | Remote (US) | Python / FastAPI / Async / Distributed Systems

Kernel is building the data backbone for commercial real estate — converting messy CRE documents into structured, decision-ready data using ML and distributed systems. It’s a $20T+ market still trapped in PDFs and siloed tools, so the impact is immediate and real.

We’re an engineering-first company — our technical breakthroughs set the direction for what we can commercialize. Our team is small, senior, and high-trust. Every engineer owns production systems and directly shapes the platform’s capabilities.

You’ll design and own backend systems powering AI-driven pipelines: async FastAPI services, SQLAlchemy 2.x models, event-driven ingestion workflows (Pulsar/Kafka), multi-tenant auth (OIDC/JWT), Kubernetes deployments, and full observability.

Stack: Python 3.12+, FastAPI, AsyncIO, SQLAlchemy 2.x, Pulsar/Kafka, OIDC/JWT, Kubernetes, GitOps/Terraform, OpenTelemetry, Prometheus.

Comp: $150k–$200k + up to 3% equity

Apply → https://kernel-intelligence.breezy.hr/p/99e076eed192-backend...

Datalab | Research Engineer, Fullstack Engineer | NYC (onsite) | Full-time

Datalab trains open-weight, state-of-the-art models for document intelligence — Chandra, Surya, Marker — used across Tier-1 AI labs, Fortune 500s, and government agencies. 50,000+ GitHub stars. 7-figure ARR. ~7× growth in 2025.

We’re a small, senior team shipping fast: everything from novel OCR models to production-grade parsing infrastructure. Tons of ownership, direct customer impact, and the chance to push the frontier of document AI.

Hiring: • Research Engineer — https://pages.datalab.to/Research-Engineer-2a2b95e8757f805da... • Fullstack Engineer — https://pages.datalab.to/Fullstack-Software-Engineer-2b5b95e...

Stack: FastAPI (Python) for backend + frontend, HTMX/JS, Postgres, Redis, Render. Training & inference in Python/PyTorch.

Benefits: Early-exercise options, full health, 401(k), unlimited PTO (incl. holiday shutdown), choose-your-own device.

Interested? Email careers@datalab.to with your resume and GH profile!

Olli Health | Remote w/ Annual Travel | Full-Time | Senior ML/NLP Data Scientist | ollihealth.ai

We are a TechStars NYC ‘24 startup dedicated to modernizing home healthcare with advanced AI tools and we are expanding our team again! These are pivotal hands-on roles that will begin shaping our product from day 1. We are backed by top healthtech and AI-focused VCs investors (Cannage Capital, Arkitekt Ventures, and Tau Ventures) and have been moving lightning fast to build incredibly valuable tools in home health.

We are looking for:

- Proven success in the fast-paced 0 to 1 early days of young startups (experience on founding team or pre-seed ideally). Work will be optimized based on your preferred balance, and what gives you energy. - Experience (5 years+) with most of our stack: AWS, PostgreSQL, Python (FastAPI), Pytorch. Role involves devops, data engineering, evals & benchmarking, workflow optimization, etc. - Able to demonstrate hands-on-keyboard coding chops. Roles are primarily IC + collaboration with our team, and room to grow into startup leadership. - Comfort interacting with ML/NLP and LLM-native data engineering problems - PhD-level ML + proven expertise training, and deploying models for production use - Experience working with healthcare data (not required but highly valued)

Comp: $185k-$230k annual FTE base comp + equity package. We cover 100% of Health, Vision, Dental, Life insurance premiums.

I’m Olli’s CTO and these positions will work directly with me and our core (currently 7-person) engineering team. hiring+hn [] ollihomehealth [] ai - Email me with questions, for a full JD, or to send your CV. No staffing or recruiting firms, please, individuals only.

Ionworks | Founding Systems Engineer | Remote (US) or Pittsburgh, PA | Full-time

Ionworks builds battery simulation and optimization software used by R&D teams designing next-generation batteries. We are looking for a founding backend / systems engineer to own big pieces of our backend and help us scale from a few early customers to broader industry use.

Work: - FastAPI, async Python, Supabase/Postgres - Designing APIs and data models for simulation and optimization workflows - Performance and reliability work across the stack (queries, async, concurrency, resource limits) - Job orchestration for running and tracking simulations - Observability: logging, metrics, tracing, debugging real issues

We are especially interested in people who work in a "vibe engineering" style: using LLMs and coding agents as accelerators, but still planning ahead, writing tests, supervising agents, and staying fully responsible for code quality and architecture. If you already use AI tools this way in your day-to-day work, you will fit in well here.

Stack: FastAPI, Python, Supabase/Postgres, distributed compute for simulations, AI-assisted dev.

Benefits: competitive salary, meaningful equity, remote-first, unlimited PTO, 401k match, medical/dental/vision, paid parental leave, home office budget.

If this sounds interesting, send a short note to valentin@ionworks.com with "HN backend" in the subject and fill in the application here: https://apply.workable.com/ionworks/j/A8C2F4287C/

The General Intelligence Company | Senior Product Engineer | Build the OS for Autonomous Agents | Full-Time | NYC | $260K - $300K + 0.3-0.41% Equity | cofounder.co

The Upside & Opportunity: Join the founding team building Cofounder, the autonomous agent platform designed to run entire business workflows (Slack, Notion, GitHub, etc.) end-to-end. We are building the operating system for one-person, billion-dollar companies. High ownership, zero bureaucracy, and maximum impact.

About The General Intelligence Company Founded in 2024, our mission is to automate business tasks. We are focused on solving the hard problem of reliable, end-to-end agent execution, turning complex LLM capabilities into dependable, real-world workflows.

You'll own the end-to-end agent experience, building and scaling Flows and Integrations. You will ship across the stack: React/Next.js (TypeScript) for novel human<>agent UX and Python FastAPI on the backend, focusing on performance and reliability. We need someone who can make powerful agent systems feel simple and reliable for users.

Stack: React/Next.js (TypeScript), Python FastAPI, Background Workers, Postgres.

If you're interested please submit an application here: https://generalintelligencecompany.cookd.dev/jobs/senior-pro...

We're also hiring an applied AI engineer! https://generalintelligencecompany.cookd.dev/jobs/applied-ai...

YCharts | Software Engineer - Applied AI | Full-Time | REMOTE (US) | 140k - 180k USD + benefits | https://ycharts.com

We're an investment research and proposal generation platform that leading RIAs, asset managers, and broker-dealers use to transform complex financial data into clear visuals and actionable insights.

I'm Carlton, the team lead for applied AI at YCharts. Our team is a full-stack software engineering team with a focus on building features that use frontier LLMs. Think AI agents and workflows that streamline the process of analyzing hypothetical portfolio allocations, building financial charts, screening for funds that match some criteria, and more.

I'm looking for full-stack software engineers who are excited about AI, but with a discerning view and an ability to cut through the hype around it to build AI features that are actually useful.

Our stack includes FastAPI, Django, Celery, Valkey, Pinecone, MySQL, Angular, and LLMs from OpenAI/Anthropic.

If you're interested, email me at cbrady at ycharts dot com with a brief intro and resume PDF or apply here: https://recruiting.paylocity.com/recruiting/jobs/Details/370...