Anterior | NYC (Midtown) | Full-time | ONSITE | https://anterior.com

Anterior is improving the experience of healthcare for everyone. We're growing fast on the cutting edge of using AI to make clinical decisioning frictionless.

About You: You have a passion for doing things The Right Way, you believe Less is More, you want to focus on Foundations of system design and architecture (pacelc, consistency guarantees), you care as much about the code you do not write, you’re tired of the hype treadmill and care about the fundamentals. You have battle scars from overengineered and underperforming slop, and you care about writing code that lasts.

- Langs: Python / Go / TS, React (and HTMX if you can help!) - Infra: Nix, CDKTF, AWS

We're hiring engineers to work directly with our end customers owning strategy and execution. The playbook for LLM-enabled enterprise software is not yet written. Come and help us write it!

Reach out directly: saul@anterior.com

GHCO - https://www.ghco.co.uk/ | Software Engineer, Senior Software Engineer, Engineering Manager, Trade Application Support | London | Hybrid | Full Time GHCO is an ETF market maker, quoting across European exchanges. We're a small team of expert traders and proven software engineers, looking for experienced technologists who have an interest in advancing the state of the art in automated market making. Tech stack we're hiring for: Java, Python, SQL, AWS

* Benefits and perks: competitive salary, health insurance, generous hardware and software allowance, casual work environment, inclusive team-oriented culture, rapid career growth opportunities, high impact work.

email: anthony dot sheldon at ghco dot co dot uk, with Hacker News in the title

ChartMogul | Remote (Europe/Asia) | Full-time

Since 2014, we have been building the leading Subscription Analytics Platform for growing SaaS businesses and CRM purpose-built for B2B SaaS teams. We're a remote-first company with 62 team members across 23 different countries. Profitable and self-sustaining since our seed funding.

What we accomplished in 2024: https://chartmogul.com/blog/chartmogul-2024-year-in-review/

Tech Stack: Ruby, Ruby on Rails, Vue.js, Typescript, Postgres, AWS

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Senior Full Stack Engineer: https://jobs.chartmogul.com/o/senior-full-stack-engineer-del...

AllSpice | https://allspice.io/ | Boston, MA / SF or Hybrid | Full time (US timezones) | Mid/Sr./Principal/Staff | Golang, Vuejs, Rust

At AllSpice, we're building the future of hardware development and collaboration, applying modern software design principles to the hardware industry with design review, automated test, and Gen AI (think GitHub/Bitbucket for hardware). AllSpice is unlocking the next generation of smart vehicles, IOT devices, rockets, medical devices, robotics, and much more.

Read more about our latest Series A announcement in TechCrunch (https://techcrunch.com/2025/06/23/allspices-platform-is-the-...)!

We have a highly capable, tight-knit, remote-first team with a flex office in Somerville, MA and SF. We strongly value continuous communication and personal development. See more on our careers page https://allspice.io/careers

We’re hiring primarily for:

Principal/Lead Software Engineer - You'll lead our platform software team (Vue, TS, Golang, Playwright), building and improving our data architecture for git-based hardware design management. https://jobs.ashbyhq.com/allspice/1dd0081e-1124-4dea-b16f-e3...

Sr./Principal Product Manager (Platform) - You'll lead our core product platform user experience, with new ECAD file integrations, collaboration features, and improved onboarding experience for git. You should have some experience in the hardware design process and git. https://jobs.ashbyhq.com/allspice/4d547ef4-e8c5-47c1-861d-15...

Sr./Principal Technical Product Manager (AI) - You've been an early adopter, introducing AI features in your past products. You understand how to tame large amounts of data for use in RAG to get consistent, functional output from LLMs, and you're not afraid to talk tensors. https://jobs.ashbyhq.com/allspice/a37723bf-b043-41b1-9365-e5...

Mid+ SW Parsing and datastructures (rust) - Systems programming experience required. You'll be responsible for helping develop our ECAD schema and convert between file formats efficiently. This role can flex to be pretty senior if you have more experience than is listed. https://jobs.ashbyhq.com/allspice/9abcef59-988f-4f1a-b4b5-c6... https://jobs.ashbyhq.com/allspice/5c889644-642a-468e-8289-3f...

Lead/Principal Infrastructure Engineer - You are passionate about optimizing infrastructure at scale and have a strong background in security engineering, AWS, and infrastructure automation. In this role, you will be responsible for working with company leadership to build our infrastructure roadmap and team, as well as executing tasks (80/20 individual contributor work to management, with greater management opportunity available as the team grows). https://jobs.ashbyhq.com/allspice/99ded9f3-4de0-420e-bedb-50...

Tech Stack: Docker, Terraform, GoLang, Rust, Python, Vue, Typescript

Please include any relevant open-source projects or portfolio in your application.

New Hedge fund | Sr IC Frontend Engineer | Full-time | On-site (NYC)

We are a new discretionary, tech industry focused L/S hedge fund, founded by a portfolio manager with 15+ years of experience at a well known Tiger Cub. I lead the data/technology team here and previously spent ~6 years in a similar role at that firm as well. We are not the only ones trying to figure out how to use AI in investing but in a world where there are lots of people trying to build picks & shovels, this is an opportunity to be one of the goldminers at a greenfield, new firm. This role makes sense for people who are interested in finance/investing (although you do not necessarily have to have experience in the industry).

We are hiring for a frontend IC engineer for our internal web application.

One of our core advantages is marrying domain experts (ie. experienced fundamental investors from top tier hedge funds) with tech talent. Our frontend (the design, the UX, the UI) _really_ matters to tie the two sides together. The quality of the data we can collect, the speed of testing new ideas, and there ultimately success is driven by the quality of our frontend -- as unintuitive as that might sound.

Our tech stack: * Frontend: Typescript, Vue3 * Backend: AWS, Cloudflare, Supabase/Postgresql, Typescript *

- We work very hard, hours are long, and people are very dedicated to the mission. It is not for everyone, but for those interested in competing in financial markets, love startup atmosphere without near-term existential risk, and want to work with super smart colleagues (both technical and investors!), this could be a great fit.

- We're in full-time in office in NYC, so that's a requirement for FTE. We are potentially open to exceptional contractors located remotely.

- Target salary 180-250K, depending on experience + Bonus/Carry (hedge fund equity equivalent)

If you are interested, I would love to hear from you:

- Contact: ai at nx1 dotcom , I'm Alex. - Please include resume or LinkedIn and some example of something you have built (could be Github, could be your current company, anything really)

If you want to learn more about types of things we think about, I will shamelessly direct you to my blog where I write about the space (and did so more while I wasn't at any fund): https://magis.substack.com

HomeCloud | Senior Cloud Engineer (AWS / Node.js / TypeScript) | Remote (US, EU UTC-6 to UTC+2) | Full-Time (Contractor)

HomeCloud is a fast-growing proptech startup rethinking home inspections, onboarding, and management using cloud-native systems and AI. We just raised a $3.5M seed round from top VCs and are building intelligent infrastructure for the future of homeownership.

We’re looking for a Senior Cloud Engineer to help us build scalable backend systems on AWS using Lambda, Step Functions, DynamoDB, EventBridge, and more. You’ll work with a modern serverless stack, integrate AI services (e.g. OpenAI, Bedrock), and help define our engineering culture alongside the CTO and founding team.

You might be a fit if you:

• Have 5+ years of experience building serverless systems on AWS

• Are fluent in Node.js + TypeScript

• Have worked with serverless architecture and event-driven systems

• Are curious about AI/LLM APIs and how to integrate them into real-world workflows

• Value ownership, pragmatism, and building useful products quickly

This is a high-impact, remote-first role on a small, focused team building the foundation of a data-rich, AI-powered platform.

Remote (UTC-6 to UTC+2)

Early-stage, fast-moving environment

Apply: https://app.dover.com/apply/HomeCloud/24919848-66d7-48c0-bf5...

Learn more: https://gethomecloud.com/about-us

CVector | Full Stack Software Engineer; UI/UX Designer | USA | REMOTE | Full-time | $75k/yr + 0.3% – 1%

CVector builds software to make energy systems smarter, more reliable, and autonomous. We integrate real-time data visualization and analytics to help power generation stations, chemical plants, and other critical infrastructure make informed decisions in rapidly changing environments. You'll help create intuitive, robust web apps and backend systems, shaping tools that directly impact industrial operations and energy reliability.

Remote-first team with occasional domestic travel to connect with users directly. Recent graduates may need to relocate.

Full Stack Software Engineer: We're looking for a passionate Full Stack Software Engineer comfortable working across our stack (Python, Typescript, React, Supabase, MQTT, Kafka, TimescaleDB, PostgreSQL, AWS).

UI/UX Designer: Explore the solution space for how users will interact with our app, and help us communicate more clearly with our customers and investors.

Reach out to me at jnapoli+hn@cvector.energy

Vendis | Senior Ruby on Rails Developer | REMOTE (EU preferred, US ok) | Full-time

• Post-MVP AI-powered B2B SaaS; serial founder-built & self-funded (pre-angel/VC), first customers onboarding – hiring employee #2. Modernizing a software category every company needs.

• Stack: Rails 8 · Hotwire (low-JS) · ViewComponents · Tailwind 4 · AWS · DynamoDB · OpenSearch · LLM APIs (zero legacy).

• You: 5+ yrs Rails, full-stack; non-relational DB + AI/LLM integration; autonomous builder & team player.

• Culture: tiny senior a-team, zero managers – you code or you sell. Values: Ownership · Pragmatism · Tempo · Kindness · No Ego.

• Comp: € 80-100 k base + € 20-25 k stock options (Delaware C-corp).

• Process: founder call → code walkthrough → 4 h remote pairing → decision in days. Apply: https://www.linkedin.com/jobs/view/4271296722/ or reply here with intro/CV + GitHub + LinkedIn.

Ploid AI | Barcelona, Spain | HYBRID (preferably on-site) | Founding Engineers | Full-time + Equity

We’re building an AI-first bioinformatics platform to empower plant breeders and life science researchers with agentic AI and LLMs. Backed by pre-seed funding and real demand from biotech and seed companies, we’re looking for versatile founding engineers to help us shape the future of AI in genomics.

What you’ll do:

• Architect and build AI workflows, agentic interfaces, and data pipelines

• Work across the stack: Go, Python, TypeScript

• Contribute to system design, infrastructure (AWS, Docker, Terraform), and devops

• Collaborate closely with scientists and iterate from prototype to product

• Help define our technical culture and roadmap as a core founding member

Nice-to-haves (not all required): LLM integration, RAG systems, gRPC, scientific computing, cloud/on-prem hybrid systems

About us: We’re an early team of engineers and scientists with strong academic and industry backgrounds (ex-BCG, PhD in Plant Biotech, M.Sc. AI). We’re committed to building something impactful, technical, and genuinely useful for life science.

Apply: hello@ploid.ai

More about us: https://ploid.ai

We also consider internship requests from strong student candidates.

GoGoGrandparent (YC S16) | FULLY REMOTE | Full-time | EST timezone | 1 x Tech Lead Engineer + 3 x Senior/Staff Backend/Full-stack/Frontend Engineers | $100k-$160k (partially location-dependent) Build high-quality, robust engineering at the rarest of things - a Silicon Valley startup that is both wholesome AND profitable. We have 8-figure revenue, are YC-backed, and growing fast.

Tech stack (required): Back-end (Node, Typescript, MySQL, REST* / GraphQL), Front-end (Vue.js), deploy (AWS, Docker/K8s)

Minimum 5 years experience (with Node or Vue).

2-stage interview process.

If you want to help older adults and people with disabilities, send your LinkedIn/CV to william@gogograndparent.com (keep it brief) or apply at https://www.ycombinator.com/companies/gogograndparent/jobs

AI x Healthcare Startup | Boston, MA Onsite | Full-time | Early Engineer

We're looking for a backend-leaning fullstack dev. You will be one of the first engineers outside of the founding team. Here is a bit more about us:

We're a seed stage AI startup backed by several top tier VCs. We're on a mission to ensure patients get the coverage they deserve from their health insurance.

We’re building deep, vertically integrated technology systems to solve fundamental problems in US healthcare - the biggest market in the world ($5T). We use AWS, K8s, React, and Rust but there is no requirement to have prior experience with them specifically.

We are a founding team made up of ex-YC, Amazon, Meta, Microsoft, and Harvard Business School with previous successful exits. We have a 6+ month customer waitlist and growing insanely fast.

We're hiring our first engineer outside the founders. You'll work directly with customers to understand their needs, design the right solution, and build from zero to one. You'll own entire parts of the roadmap and tech stack while wearing multiple hats. Most important characteristics are resilience, work ethic, and curiosity. We care about slope, not where you are today.

This is an opportunity to work in an insanely fast paced, high ownership environment while solving real problems in healthcare. We're happy to share more details on the role in person/on zoom. Please fill out this form if interested!

https://wgwx7h7be0p.typeform.com/to/LV0t8OjI

Connie Health | https://www.conniehealth.com/ | Multiple engineering roles | Hybrid (Boston, MA) | Full-time

Connie Health is a fast-growing healthtech startup on a mission to empower older Americans to make confident, worry-free Medicare plan decisions. We offer a tech-enabled Medicare navigation platform that combines an AI-driven technology with local Medicare experts to help people select optimal healthcare plans and navigate their benefits. Our culture is mission-driven, collaborative, and innovative, as we strive to transform healthcare through data-driven insights and personalized guidance.

We are building a two-sided marketplace, connecting older Americans looking for health insurance with local Medicare agents.

We are looking to fill multiple positions on our rapidly growing engineering team, based out of Boston, MA:

Senior Backend Engineer (Call Infrastructure) | $130,000 - $156,000 + Equity

Responsibilities: Lead the development of our Twilio-based calling + messaging infrastructure, enabling seamless communications between Medicare agents and customers. You must have significant experience with Twilio. Tech Stack: TypeScript + NestJS, Twilio / Five9 / Zoom, Postgres, AWS, Docker + Kubernetes

Lead AI/ML Engineer | $152,000 - $182,000 + equity

Responsibilities: Player-coach role, leading a small team of AI/ML and software engineers to build our top-of-funnel systems. Tech Stack: Python, "traditional" AI/ML model building tools (scikit-learn, PyTorch, XGBoost), open source LLMs, AWS, Aurora/Postgres, Redshift

Senior Backend Engineer | $130,000 - $156,000 + equity

Responsibilities: Build the core backend systems that power our top-of-funnel, such as tracking leads through various channels, integrating with affiliate partner marketplaces, working with AI/ML engineers to build our lead bidding models, dynamically mapping leads to agents, and AI-based lead pre-qualification. Tech Stack: TypeScript + NestJS, Postgres, AWS, Docker + Kubernetes

I am Huan, CTO at Connie Health. If you are interested, please feel free reach out to me directly at with your resume: huan.lai (at) conniehealth.com !

BillionToOne (YC S17) | Menlo Park, CA; on-site or hybrid (US only) | Full-time BillionToOne is ranked at the top 5% of Y Combinator companies with close to $400M in funding. In June 2024, we closed a $130M Series D resulting in a company valuation of over $1 billion. This funding has come from prestigious global institutional investors, including Hummingbird, Adams Street Partners, Neuberger Berman, Baillie Gifford, and Premji Invest.

We have developed a DNA molecular counter that increases cfDNA diagnostic resolution by over 1,000x. Our first product, Unity, is the first and only non-invasive prenatal test that can directly screen an unborn baby and assess its risk for: common and severe recessive gene disorders; chromosomal abnormalities; fetal sex; and fetal antigens from a single tube of blood from the pregnant mother. This greatly improves the quality of care and is on its path to becoming the next standard-of-care.

Our software stack includes Python/Django, React/Typescript, Terraform, AWS, and many other standard tools. We're a small, but nimble software team that prioritizes rapid iteration and continuous feedback to evolve our product. As a biotech company, we inherently need to always work cross functionally. If you enjoy this style of work, please reach out!

We're hiring software engineers, bioinformatics engineers, and many other roles. You can email me directly at kwu@billiontoone.com with your resume or apply through the links below.

- Senior Software Engineer, Frontend: https://job-boards.greenhouse.io/billiontoone/jobs/436548500...

- Senior Bioinformatics Engineer, Prenatal: https://job-boards.greenhouse.io/billiontoone/jobs/449603100...

- Director, AI Engineering: https://job-boards.greenhouse.io/billiontoone/jobs/449575500...

- Director of IT: https://job-boards.greenhouse.io/billiontoone/jobs/455290000...

You can view all open roles on our careers page: https://billiontoone.com/careers/open-positions/.

Range | Mclean, Virginia - On-site | Full Stack Engineers (Senior/Staff/Principal) | Full-time https://www.range.com/public/careers

We're building the first AI wealth platform and hiring full stack engineers to partner closely with our co-founders and engineering leadership. We're a Series B company with 70 people all passionate about making wealth management better, faster, for every household. We're open to relocating candidates. Email me (tyler at range dot com) if you're interested to learn more.

Stack: Nodejs, Graphql, React, Typescript, AWS Comp: $150 - 250k base + equity

Trustle | https://trustle.com | Senior/Staff Backend Engineer | Remote (US time zone preferred) | Salary based on experience and location We're building the future of cloud access management - helping companies achieve Zero Standing Privileges through just-in-time access and intelligent entitlement management. What you'll work on:

Build intelligent scheduling engines that orchestrate just-in-time access across thousands of cloud resources Design AI-powered systems that help customers intelligently request and review access across AWS, GCP, Azure, and SaaS platforms Create scalable integration pipelines using durable functions to connect with dozens of cloud providers and enterprise tools Develop next-generation data models that map complex permission relationships across multi-cloud environments Work with AI coding agents to accelerate development and ship features faster

What we're looking for:

Strong Python experience (FastAPI is a plus) Experience with data modeling and building complex ELT pipelines at scale Postgres experience and familiarity with BigQuery API design and development expertise Comfort with cloud platforms and Identity and Access Management concepts Data lake architectures and Kubernetes experience is a plus

Feel like you are up for a challenge? We'd love to see you complete our coding challenge here: https://github.com/trustle/task_challenge or reach out to us at careers@trustle.com

Cribl | https://cribl.io/careers | FULLY REMOTE | We have a lot of positions open.

Backend, Frontend, SRE. Mostly a node.js shop.

I'm hiring for a Senior Staff Engineer https://cribl.io/job-detail/5596071004/

Node.js, big data, streaming, distributed systems architectures, AWS.

We also have a lot of other roles open

https://cribl.io/careers/engineering/?department=Engineering

Spacelift | Remote (Europe) | Full-time | Senior Software Engineer | $80k-$110k+ (can go higher)

We're a VC-funded startup building an infrastructure orchestrator and collaborative management platform for Infrastructure-as-Code – from OpenTofu, Terraform, Terragrunt, CloudFormation, Pulumi, Kubernetes, to Ansible.

On the backend we're using 100% Go with AWS primitives. We're looking for backend developers who like doing DevOps'y stuff sometimes (because in a way it's the spirit of our company), or have experience with the cloud native ecosystem. Ideally you'd have experience working with an IaC tool, i.e. Terraform, Pulumi, Ansible, CloudFormation, Kubernetes, or SaltStack.

Overall we have a deeply technical product, trying to build something customers love to use, and have a lot of happy and satisfied customers. We promise interesting work, the ability to open source parts of the project which don't give us a business advantage, as well as healthy working hours.

If that sounds like fun to you, please apply at https://careers.spacelift.io/jobs/3006934-software-engineer-...

You can find out more about the product we're building at https://spacelift.io and also see our engineering blog for a few technical blog posts of ours: https://spacelift.io/blog/engineering

Additionally, we're hiring for a new product we're building, Flows[0]. Mostly the same requirements and tech stack, without the devops bits. If you'd like to apply specifically for that, just mention "new product" in the cover letter field.

[0]: https://events.spacelift.io/devops-next

Clerq | Senior/Staff Engineer | onsite (NYC) | https://clerq.io

Clerq is a NYC based fintech startup building the next generation platform payments platform delivers a seamless checkout experience for high-ticket transactions. By leveraging modern bank rails, the platform offers the conversion and UX benefits of cards with risk and money movement infrastructure purpose-built for large purchases. Clerq replaces outdated manual payment methods like cash, checks and wires and expensive card surcharges with a smooth, integrated solution that helps merchants convert more customers without sacrificing margins.

We have started with the $1T+ U.S. auto vertical, where our platform is growing rapidly and already powering payments for several of the most recognized brands in the industry including multiple Fortune 500 companies. With proven traction, the company has expanded into high-growth adjacencies including high-ticket e-commerce, private travel and powersports.

We are a lean team and looking for senior or staff level engineers to help us accelerate our growth and build a future that doesn't rely on credit card networks.

Stack: Python/Django, React, Nodejs, AWS Comp: $180-210k + Equity

Email me at nick@clerq.io if you are interested in hearing more!

Littlebird | Senior MLE + Senior Swift Engineers | Remote (global) | https://littlebird.ai/

Littlebird is working on a digital twin for Mac + Android to make anyone more productive, no matter what apps they use. Our team is well funded (~$5M+ seed) and remote-first, and passionate about building a product anyone can use. We're hiring developers with a passion for engineering-led cultures, knowledge graphs, search, contextual understanding, and designing infrastructure that can scale.

Core stack: Typescript, React, Swift, python, Postgres, AWS, some Rust

Apply here:

Senior Applied AI Engineer: https://scarlet-magician-747.notion.site/Senior-AI-ML-Engine...

Senior Swift Engineer: https://scarlet-magician-747.notion.site/Senior-Swift-Engine...

Opsin Security | San Jose / SF Bay Area (Hybrid, 2–3 days on-site) | Full-time | https://opsinsecurity.com/careers

Opsin helps enterprises secure and deploy Enterprise Search/AI systems (e.g. Microsoft Copilot, Google Gemini) responsibly without exposing sensitive data. Venture-backed by Race Capital. You’ll work directly with the founders on a small (<10) person team shipping fast in a huge green-field space.

We are hiring for:

- Senior AI Engineer – 5 + yrs backend + 2 + yrs ML/LLM; Python, SQL, AWS/GCP experience; comp + eq (https://www.opsinsecurity.com/jobs/senior-engineer-ai-engine...)

- Senior Full-Stack Engineer – 4–8 yrs shipping product; React/Next.js + API & DB design + Nest.js; TypeScript, Python a plus; comp + eq (https://www.opsinsecurity.com/jobs/senior-engineer-full-stac...)

- Staff Backend Engineer – 8 + yrs building scalable systems + 2 + yrs technical leadership; architect data-driven services for LLM security; comp + eq (https://www.opsinsecurity.com/jobs/staff-engineer-backend)

- Founding Account Executive – full-cycle sales to CISOs/CIOs; 5 + yrs enterprise SaaS; cybersecurity/Microsoft ecosystem a plus; ~50% travel; comp + eq (https://www.opsinsecurity.com/jobs/founding-account-executiv...)

Tech stack: Python, TypeScript (Nest.js), React (Next.js), Postgres, Azure, modern LLM tooling

How to apply: email your résumé + a short note to careers@opsinsecurity.com with subject “HN – [role]”, or apply on our careers page.

I’m Shay Nehmad, Founding Engineer at the company. Happy to answer questions at shay@opsinsecurity.com or on LinkedIn