Standard Model Bio | various | Full-Time | ONSITE SF or Philadelphia | Hybrid

we're building the standard model for bio. We're doing for biology what mathematics did for physics.

we're humble and ambitious - we want to be the quiet backbone of biomedical ai but we want none of the glory of the final applications.

standardmodel.bio

kevin@standardmodel.bio

StorPool | Senior Software Engineer - Storage Core (C/Linux) | Remote (UTC-1 to UTC+5) | Full-time | Multiple roles StorPool is building the future of data storage. Our software runs at the heart of modern clouds, delivering <100µs latency, 113M+ IOPS per cluster, and 99.999% availability. We're profitable, self-funded, and our customers love us (NPS off the charts).

We're looking for a Senior Software Engineer to join our Core Storage team. You'll tackle genuinely hard problems: writing custom Linux drivers, optimizing lock-free data structures at nanosecond scale, building fault-tolerant distributed algorithms, and debugging issues that go all the way down to kernel internals. This isn't CRUD work - it's systems programming at its most challenging.

Competitive salary, fully remote, meaningful time off, and a yearly education budget to keep learning.

If you get excited about shaving microseconds off I/O paths and building infrastructure that simply doesn't break, we should talk.

Apply here: https://storpool.com/force/senior-software-engineer-storage-...

Ledgebrook | https://www.ledgebrook.com | Multiple roles (Engineering, Data, IT/Security, Product) | REMOTE (US, Canada, Poland ET-friendly) | Full-time | Visa: Not available

We’re a tech-enabled E&S MGA on a mission to modernize Specialty insurance. The industry is burdened with legacy technology and inefficient processes, preventing innovation at scale. We are changing that. Our goal is to become the best-in-class full-stack insurance and re/insurer, leveraging AI and data-driven insights to revolutionize underwriting, pricing, and risk selection. We believe in talent density—fewer, better people working together as one. We win as a team.

Open roles:

• Engineering Manager — https://app.careerpuck.com/job-board/ledgebrook/job/77.E51

• Fullstack Software Engineer (Backend, Python/TypeScript) — https://app.careerpuck.com/job-board/ledgebrook/job/08.75A

• Data and Analytics Engineer (Snowflake/dbt/Airflow) — https://app.careerpuck.com/job-board/ledgebrook/job/77.E5D

• Machine Learning Engineer — https://app.careerpuck.com/job-board/ledgebrook/job/77.E59

• Head/Director of IT & Security (SOC 2/IdP/MDM) — https://app.careerpuck.com/job-board/ledgebrook/job/77.E58

• Product Manager, Data and Infrastructure — https://app.careerpuck.com/job-board/ledgebrook/job/67.E5E

Our stack (role-dependent): Python, TypeScript/React, FastAPI, Node; Postgres, Snowflake, dbt, Airflow; AWS (ECS Fargate, S3, CloudFront, Route53, Secrets Manager), Terraform; Bedrock, LangChain/CrewAI; PowerBI

Requirements (vary by role): Strong ownership and bias for action; clarity in written communication; hands-on delivery in lean teams; comfort with ambiguity and high standards. Deep experience with one or more areas above (shipping production systems, data pipelines, LLM apps, or secure/AWS infra).

Benefits: Competitive comp + equity, medical/dental/vision, PTO, remote-first with periodic team onsites.

Apply: email hiring@ledgebrook.com with subject “HN: — ”. Please include a brief note on why Ledgebrook, a recent project you’re proud of, and your LinkedIn/GitHub. We’re actively hiring and will respond to applicants.

BuildBetter | Senior Engineer (Backend, Full-stack) | Full-Time | Remote (US) 170-200k base + equity | Visa Sponsorship not provided

BuildBetter is the product operations platform for customer-led teams. We've built an AI-first product that lets our customers, like Rappi, n8n, and Posthog, automate the operations work that lets them provide their customers with world-class product experiences.

We're looking for two senior engineers to join the team; our headcount has remained small while growing revenue, and we're now bottlenecked by development speed in a way that will make you invaluable. You'll have real ownership over your code from product ideation to customer support, and we'll be making substantive product updates weekly. We're looking for team players who are as fun to work with as they are productive, and are willing to compensate these two rolls commensurately - our aim is to be in the 95th percentile of equity compensation, and we expect that in exchange we'll have value-aligned employees who will help us grow the business.

Joining us will mean solving hard problems at the frontier of AI adoption, including:

- maintaining performance at scale

- building agent and workflow systems that automate real work for customers

- playing around with the latest models to figure out new experiences that we can offer our customers as cutting-edge models get released monthly

- building automation that's grounded in supporting product teams rather than automating them - our bet is that this is the likelier outcome out of the current generation of AI systems

Stack: Postgres / TS (Nest + React) / Hasura / EKS / S3 / LLM APIs / Python

Benefits:

- unlimited PTO

- $100/mo education stipend

- flexible hours: we measure productivity in terms of outcomes, not time, so as long as you're able to stay aligned, productive, and in regular communication, we don't really care what hours you work

Please reach out at:

nikhil (at) buildbetter (dot) app

This may not be the “right” place to ask this, but I am a software engineer in the entertainment industry and it’s pretty bad right now. What is a pivot I can make? My skills are mostly C++ and Python.

Surge AI (https://surgehq.ai/careers) | Software Engineers (full-stack / product) and Strategic Project Lead, and many more https://surgehq.ai/careers | Full-time | ONSITE SF or NYC | Remote

Our mission at Surge is to build the human infrastructure behind the next wave of AI and LLMs. We operate the largest human data platform in the industry and power the AI teams at all of the top AI labs. This year, we've been focusing on RL environments and agentic workflows to help our clients ship agents that interact with the world. Here are some examples of our past work:

- Creating the GSM8K dataset: https://www.surgehq.ai/blog/how-we-built-it-openais-gsm8k-da...

- Collecting RLHF data for Anthropic's Claude: https://www.surgehq.ai/case-studies/anthropic-claude-surgeai...

You’d be joining a rapidly growing team of former engineering and ML leaders from Google, Meta, Twitter, and Airbnb. We work in small groups, ship quickly, and value autonomy and ownership. No previous AI experience is required, if you have the engineering skills you can learn what you need on the job.

We're looking for senior engineers to work out of our offices in SF or NYC, or remotely. Please reach out to us at careers@surgehq.ai with a resume and 2-3 sentences describing your interest. Excited to hear from you!

MITTE.AI | Berlin, Germany | REMOTE (Europe/+- 2h timezone) | FULL-TIME | AI Creative Suite

We're building an AI Creative Suite that empowers creators with cutting-edge AI models and an advanced editor.

Join our team in Berlin or work remotely within +- 2 hours of our timezone (Europe, Türkiye welcome).

MITTE IN ACTION

https://x.com/azerkoculu/status/1945391849989976533

https://x.com/MaxVOAO/status/1961441059235352579

TECH STACK

Go, Elixir, TypeScript, React, Redux Toolkit

ROLES

Senior Frontend Engineer: https://mitteai.notion.site/Senior-Frontend-Engineer-258f3cd...

Senior Elixir Engineer: https://mitteai.notion.site/Senior-Elixir-Engineer-258f3cdf0...

Senior Full-Stack Engineer: https://mitteai.notion.site/Senior-Full-Stack-Engineer-258f3...

Speckle | Backend (Engineering), Founding Account Executive (Growth) | Full-Time | REMOTE | US East, London, EU | https://jobs.ashbyhq.com/speckle

At Speckle [0], we’re on a mission to shake up the AEC (Architecture, Engineering, and Construction) industry. To do that, we're building the OSS data layer for AEC to operationalize how the built environment industry works with data and automation. Think of us as a cross between Github and Palantir, with an opportunity to significantly impact a $10 trillion industry. Our platform already powers workflows on billion dollar projects at leading firms like Suffolk, Multiconsult, Pomerleau, and Stantec.

I'm the CEO/founder and I can honestly vouch that we're tight knit team that values autonomy and shipping cool product on top of our data layer (me included - and this might be a red flag for some, but it's my therapy) over hierarchy, politics, levels and complexity (my spirit animal is the grug brained developer). We love working together with our customers - construction is truly a unique place where each project is its own micro universe.

We have multiple roles open across engineering and growth (sales & marketing) [1]

[0] https://speckle.systems/about [1] https://jobs.ashbyhq.com/speckle

Mercanis | Hiring in Berlin or Remote EU (role dependent)

About us: Mercanis is building the Agentic AI Procurement Suite, enabling enterprises to automate procurement and supplier management workflows using AI. Backed by $30M+ from Partech, AVP, and Speedinvest.

⸻

Engineering Manager | Berlin, Hybrid Lead a cross functional product engineering team, work across the stack, and stay hands on (>20% contributing code). Collaborate closely with product and design to deliver user centric, scalable software. Tech includes Svelte, TypeScript, Node.js, NestJS, AWS, Postgres.

You have: Strong engineering background, 2+ years managing or leading engineers, experience with modern web stacks, a pragmatic and collaborative mindset. Berlin based, hybrid with flexibility for occasional remote days.

⸻

AI Agentic Engineer | Remote EU or Berlin/Barcelona Hybrid Build AI agents that automate procurement workflows across large enterprises. Work deeply with LLMs and orchestration frameworks, evaluate and integrate models, and ship production AI features. Tech includes Python, LangChain, AWS, OpenAI, Anthropic, and Bedrock.

You have: Strong applied AI experience, experience building agentic or multi step LLM workflows, familiarity with enterprise grade systems, passion for fast iteration and quality.

⸻

Technical Product Manager, Integrations | Berlin, Hybrid Own the integration strategy for enterprise procurement systems, especially SAP S4HANA and SAP Ariba. Work closely with engineers and enterprise customers to deliver scalable APIs and integration architecture. Translate complex business workflows into clear product requirements.

You have: 5–8+ years in Technical PM, Solutions Engineering, or Integrations, experience with ERP or procurement systems, strong API and data integration understanding. Berlin based, hybrid with flexibility for occasional remote days.

⸻

Apply: https://mercanis.jobs.personio.de/ More about us: mercanis.com

If you believe in ownership, iterative delivery, and building modern enterprise software the right way, say hello.

Domos | NYC | Software Engineer | AI + Real Estate Ops

We’re building an AI workforce for property management, automating workflows and processes, such as resident communication, leasing, and document processing through email, voice, and integrations (Yardi, Rent Manager, CRMs, etc.). We’re NYC-based, venture-backed, and growing fast, now looking for a backend engineer excited to build AI products that run in production and have immediate impact.

Looking for: someone with 2+ years of backend/Python experience, ownership mindset, and strong product/user experience instincts. You’ll: build real product used by thousands of residents, own core systems, and work directly with the founding team (product + sales). More details here: https://joindomos.com/careers/software-engineer

Prophet Town LLC | Various Software Engineering Roles | US – Remote and Hybrid | English fluency required | Full-time | $150K-$250K annual total comp (multiple)

I’m the founder, trying to do “enlightened business.” We are a people-first, fully-remote, boutique indie tech agency – building a team of talented, high integrity, and community-minded individuals first, then building businesses around them. Our leadership staff are ex-Fortune 100; everybody touches code. Notable recent projects: internal tools for Anduril, and voltagepark.com.

We’re currently especially seeking:

Frontend Engineers (React, NextJS, Typescript; Animations, Performance optimization; sfbay local a plus)

Teamcenter and Odoo developers (C++/Java/Python; Siemens Teamcenter; Custom applications, workflows, data model updates)

IoT Developers (Python, MQTT, GraphQL, AWS, Test Infrastructure)

Full-Stack Software Engineers (React, Python, Ruby on Rails; Database Design, Devops, and third-party API integrations)

Please apply using this Google Form: https://forms.gle/oJHSjofaxTjSPexW8. Applicants who submit before November 14 will typically receive a reply by November 21. Tier3 roles are typically 5-10 y/o/e with $150-$175k annual total comp. Tier4 roles are 11-20 y/o/e, $210-$250k annual total comp. Higher tiers exist, and we welcome exceptional applications.

BIASafe AI | Front-end Engineer (React) | Full-Time | ONSITE (Montréal)

We're building a B2B digital quantitative portfolio manager platform for family offices and hedge funds. Our platform allows portfolio managers to create, backtest, test and execute systematic quantitative trading strategies. We are currently closing our seed round.

We are looking for a front-end developer to join us IN PERSON at our brand new offices in downtown Montréal's FinTech Station. The ideal candidate will have 3+ years of experience in React as well as a strong sense and ability for design. Good general software engineering knowledge is also a must. The candidate will work in a small team and own the front-end development, mocking, CI/CD, support and maintenance. We have a very highly detailed Figma model and we are looking for the right talent to bring it to life.

Interested applicants should contact me at mabelanger + hn at biasafe dot ai. Please put our exact company name in the subject line. Please send a CV along with a short introduction and I will do my best to get back to you ASAP!

Float Technologies | Backend, Financial, AI Engineers | Full-Time | ONSITE | New York, New York | $120k-225k https://www.float.tech/careers

At Float, we're building capital markets infrastructure. Our AI-native platform is tackling decades-old inefficiencies, creating technology that enables financial institutions to interact seamlessly and automate intelligently. Based in SoHo, New York and backed by top-tier venture investors, we're a team of engineers, designers, product managers, quants, and market experts shipping elegant solutions to complex problems. We move fast, care deeply about building things right, and work directly with our users to deliver products that transform how markets operate.

If interested, apply here https://float-tech.notion.site/140ab6ef153b800a97e0d68ee5444...

Fliki.ai (AI-powered video editor) Dubai, UAE / Bangalore, India | ONSITE | Full-Time With recent advances in generative AI, we are reimagining the product around a simple idea: AI is the new UI. We're a team of only 5 and looking to carefully add a couple of full-stack engineers onboard.

What you'll be working on: https://fliki.ai/whats-new/sneak-peek-v4

Email: atul (at) fliki.ai

Source (https://source.network)| USA/Canada/EU: REMOTE | Full-Time | https://source.network/careers At Source, we aim to revolutionize developer data management for the open web. Our mission is to simplify data handling for edge devices, local-first software, and distributed infrastructures, allowing developers to unleash their creativity and build world-changing tools that realize the open web’s full potential.

Our suite of new technologies work together to make it easy for developers to ship edge and local-first software. We empower developers to create software and devices that seamlessly communicate, offer granular data control, and secure data cryptographically to ensure trust. Join us in shaping the future of data management and the open web.

We’re growing fast and are looking to fill the below positions:

ENGINEERING

- Chief of Staff - https://source.network/careers/chief-of-staff

- Lead Edge AI Engineer - https://source.network/careers/lead-edge-ai-engineer

- Lead Technical Writer & Documentation Engineer - https://source.network/careers/lead-technical-writer--docume...

- Head of Developer Relations - https://source.network/careers/head-of-developer-relations-r...

- Senior Zero-Knowledge Engineer - https://source.network/careers/senior-zero-knowledge-enginee...

- Protocol Engineer (Distributed Systems) - https://source.network/careers/software-engineer-backend-dat...

- Software Engineer, Backend (Database/Distributed Systems) - https://source.network/careers/software-engineer-backend-dat...

See all our open positions here: https://source.network/careers

Aviagen | Full-Stack Software Developer | Huntsville, AL (onsite) | Full-Time

Aviagen, a global poultry-breeding company supplying pedigree lines for broiler production, is looking for a Full-Stack Software Developer who loves building tools that users actually use and benefit from.

What you’ll do:

- Architect and build web apps that replace legacy systems, streamline business processes, or replace paper or excel based workflows. So far, our web-apps are vanilla JS, with C# / ASP.NET Core backends. We're open to JS frameworks where appropriate.

- Collaborate directly with stakeholders to identify pain points and deliver impactful solutions.

- Own the end-to-end lifecycle: idea, design, implementation, deployment, support.

What we need:

- 5+ years of software development experience, comfortable across front-end and back-end.

- Solid JavaScript/TypeScript skills, experience with REST APIs, relational databases.

- Enthusiastic about owning features, interacting with users, improving business workflows.

What we offer:

- Competitive salary + bonus + company benefits (details on request).

- Real ownership and visibility within a global company with the feel of a smaller team.

- Located onsite in Huntsville, AL - full-time. (Hybrid/remote not currently available.)

How to apply:

Send your resume to dmurph@aviagen.com - mention “HN Who’s Hiring” in the subject. Or apply via https://aviagen.wd1.myworkdayjobs.com/en-US/aviagen-careers/...

Also hiring:

- IT Data Analyst - help build dashboards and data tools for global ops: https://aviagen.wd1.myworkdayjobs.com/en-US/aviagen-careers/...

- Database Administrator (DBA) - manage and optimize our critical data systems: https://aviagen.wd1.myworkdayjobs.com/en-US/aviagen-careers/...

PrairieLearn (Remote US) — Full-Stack Software Engineer — TypeScript / Node / Postgres / AI

PrairieLearn (https://www.prairielearn.com) is an open-source assessment platform originally developed at the University of Illinois and now used by universities across the US (Berkeley, Princeton, Michigan, UIUC, and others). We power mastery-based learning, interactive question generators, and large-scale exams.

We’re a small, profitable, early-stage company (bootstrapped, no VC) and we’re hiring a full-stack engineer to help us continue to grow. You’ll work across the stack and have meaningful ownership from day one.

We’re also developing AI tooling in the product:

* LLM-based agents to help instructors create and test new question generators

* Vision-language models for grading student-submitted work (e.g., math derivations, diagrams, sketches)

This is practical, user-facing AI work with real-world impact — not a research sandbox.

Tech we use:

* Node.js / TypeScript backend, Postgres, AWS, React

* PrairieLearn is open core: https://github.com/PrairieLearn/PrairieLearn

You might be a fit if you:

* Have experience with full-stack web development (TypeScript / Python / SQL / HTML/CSS)

* Enjoy working directly with users (many are instructors and TAs)

* Want to own features end-to-end, from idea to rollout

* Are excited about building practical AI integrations, not just demos

Details:

* Location: Remote (US only)

* Salary: $100k+ depending on experience

* Benefits: Stock options, unlimited PTO, flexible hours

* Role: Full-time. (We’re not able to sponsor visas at this time.)

If this sounds interesting, please email jobs@prairielearn.com. We’d love to talk.

Official job posting: https://www.prairielearn.com/jobs

Pickaxe | Founding Typescript Engineer | Full-Time | In Person (SF)

Pickaxe (https://pickaxe.co/) allows coaches and consultants to build chatbots and agents for their clients. We're a small committed team of hackers focused on building a beautiful product for our customers. We just raised our seed and we're making our 3rd and 4th engineering hires.

Learn more here: https://pickaxe.co/careers/full-stack-engineer

Nettle (https://nettle.llc/) | REMOTE | Autonomous Data Processing | Compensation and Culture: Netflix rules - Top of personal market for your role and geo, stunning colleagues.

We're building an autonomous data processing system to make data engineers 10x+ more effective.

Currently open roles: ----------

Principal Product Manager https://www.linkedin.com/jobs/view/4319438984/

Staff or Senior Staff Tech Lead / Engineering Manager (Data Infrastructure) https://www.linkedin.com/jobs/view/4319530325/

Senior Marketing Executive https://www.linkedin.com/jobs/view/4317950237/

---------------- Please apply on LinkedIn if these sound interesting!

Logiqo Inc. – Full-Stack Engineer (AI-focused, remote, CET!)

We’re developing an AI assistant for iGaming/Betting and have good commercial traction. Looking for a curious builder who embraces AI and likes to ship.

Business platform stack is Java/Spring Boot and PostgreSQL. Experience with LLMs, embeddings, prompt engineering and AI ops preferred.

You are independent, motivated and embraced AI in your workflow.

Reach out to oliver@promptbet.ai