Colonist | Senior Product Engineer, QA Engineer | Full-time | Remote & async

Colonist (colonist.io) is a multiplayer board game platform. ~20 people, millions of monthly players, no middle management between you and the product.

You'll own features end-to-end and ship to a live player base within days. Right now we're evolving the core experience and building toward a multi-game platform. The mission is to become the internet's biggest board game platform.

This role is a good fit if you: want to see your work matter at real scale without a large team around you, are comfortable with ambiguity and don't need someone to define your tasks, and use AI tools as a genuine multiplier in your workflow.

This isn't a good fit if you: prefer a larger team with specialists for every layer, or are looking for a role with clearly scoped tickets.

More on the roles, culture and values: https://jobs.ashbyhq.com/colonist

Radical Numerics | San Francisco, ONSITE (also Tokyo for some roles) | Full-time | https://jobs.ashbyhq.com/radical-numerics

Radical Numerics is an AI research lab building general biological intelligence. We're bringing the rigor of distributed systems, model architecture, and numerics research to biology. Our team created Evo and helped start the field of generative genomics — our work has been on the cover of Science, featured in Nature, and presented at TED2025. We're now scaling our research and infrastructure teams to build the next generation of scientific world models.

Open roles:

Head of Data Acquisition — San Francisco, ONSITE Member of Technical Staff, AI Supercomputing — San Francisco / Tokyo, ONSITE Member of Technical Staff, AI Bio — San Francisco, ONSITE Member of Technical Staff, Biosecurity — San Francisco, ONSITE Member of Technical Staff, Computational Biology — San Francisco, ONSITE Member of Technical Staff, Inference — San Francisco Member of Technical Staff, Infrastructure and Training Systems — San Francisco / Tokyo, ONSITE Member of Technical Staff, Mechanistic Interpretability — San Francisco / Tokyo, ONSITE Member of Technical Staff, Post-Training — San Francisco / Tokyo, ONSITE Member of Technical Staff, Pretraining Science — San Francisco / Tokyo, ONSITE

Apply here: https://jobs.ashbyhq.com/radical-numerics

We are hiring full-stack and applied AI engineers, as well as a UI designer, for in-person roles in NYC.

Our product helps everyone make better legal decisions by better understanding the law. About one-third of important U.S. law is not accessible via ChatGPT or Claude. Much AI-generated legal analysis is wrong. We are building one of the largest collections of U.S. law in existence and using AI to make it make sense.

We are a seed-stage start-up, still in stealth (but already with an acquisition offer!), backed by tier-1 VCs and many of the most prominent experts in legal technology. We are working with several of the best law firms in the world. We have strong customer demand and need people to help us fill it. We are committed to improving access to justice.

We are hiring a small team of extremely talented, motivated, intense, and interesting people to solve the most difficult and important problem in legal tech: high quality answers to legal questions. Expect market-leading compensation, including meaningful equity ownership. Please send your resume to contact[at]ashmere.com. We are ONSITE only in NYC.

MWI Animal Health | Remote (US only) | multiple roles

MWI Animal Health is a leading U.S. distributor of animal health products, medications, and technology solutions for veterinarians and livestock producers.

1. Senior Application Developer (React + Composable Commerce)

We're hiring a senior dev (8+ yrs) to lead projects, mentor juniors, and build scalable apps end-to-end. Stack: React (Redux/Context), C#/.NET, microservices, headless commerce (CommerceTools, ContentStack), NoSQL + relational DBs, event streaming, TDD. You'll turn messy business requirements into solid technical solutions and help shape our architecture. Bonus: WMS experience. Apply if you like leading, mentoring, and shipping.

2. QA Engineer

We're hiring a QA Engineer to own quality across our suite of connected web applications and the shared services between them. You'll mix hands-on manual/exploratory testing with building and maintaining automated suites (end-to-end, integration, component), with a big focus on the seams between apps: navigation, shared auth, data hand-offs, and micro-frontend integrations. You'll own the full bug lifecycle, wire tests into CI/CD as reliable quality gates, and partner with product and engineering to build testability in from the start.

Ideal fit: 3+ years in QA testing web apps, across both manual and automated testing with modern frameworks (Playwright, Selenium) and unit/component tooling (Jest, Vitest). Comfortable testing SPAs and REST APIs, with enough JavaScript/TypeScript to write and debug test code. Bonus points for React, Vite, monorepos, micro-frontends, GitHub Actions. Above all, a user-focused mindset — catching problems before customers do.

3. Senior DevOps Engineer

We're hiring a Senior DevOps Engineer to standardize application deployments, containerization, and release processes across our org. You'll build shared CI/CD pipelines, containerize apps with Docker/Kubernetes, and create the tooling and golden paths that let teams ship reliably. Ideal fit: solid experience with CI/CD (GitHub Actions/GitLab CI/Jenkins), IaC (Terraform/Helm), and cloud providers (AWS/Azure), plus a track record of driving standardization at scale. Pragmatic, collaborative, and motivated by making other teams more productive.

For all of these roles, reach out to Alex at [Alex.Heck] (at) {cencora} (dot) [com]

Relevant Healthcare | Software Engineers (multiple levels) | Remote (US/Canada) | Full-time

Relevant builds a data platform that helps safety-net healthcare providers deliver better care using data from their electronic health records. Our customers are non-profit clinics called Community Health Centers. You can read more about them, us, and the roles on our jobs page: https://relevant.healthcare/jobs/ We're a small team (~25 overall). We're bootstrapped (no external capital whatsoever, VC or otherwise) and profitable. We've got a modern tech stack (Rails, Typescript, React, GraphQL, d3) and a healthy approach to both tech debt and work/life balance… and we’re also a very nice group of people that get to work on interesting problems for some of the few unimpeachably good actors in healthcare!

Johns Hopkins Applied Physics Laboratory (JHU APL) | Graphics Software Engineer | Laurel, MD | ONSITE | Full-time | Secret clearance | $105k-$290k | https://careers.jhuapl.edu/jobs/59329

APL is hiring a Graphics Software Engineer to help build EO/IR and multispectral rendering software for integrated air and missile defense simulation and analysis. This is applied R&D/engineering work on a small multidisciplinary team supporting high-impact national security programs.

Looking for someone with strong C++ and GPU/rendering experience: low level graphics APIs; shaders; rendering pipelines; 3D geometry/linear algebra; performance-sensitive software; profiling/optimization; and experience working in large codebases.

Apply: https://careers.jhuapl.edu/jobs/59329

PostHog | Full-Time | Product engineers, Technical CSMs, Technical AEs | REMOTE (all remote) | Hiring GMT-8 to GMT+2 PostHog makes dev tools that help product engineers build successful products.

* we have a public handbook (posthog.com/handbook) if you want to learn how we work, pay and more in complete detail.

* we are growing through more autonomy and transparency not through process.

* we have a ton of scale and a bunch of super interesting technical problems to solve

* we're building 20 more products over the next couple of years, so you could end up building one of those

* public compensation calculator! see immediately what you'd get paid

* we're hiring: product engineers, clickhouse operations engineer, backend engineers, technical customer success managers, technical account executives, developer marketers, bdr team lead, rev ops manager, and more.

https://posthog.com/careers

[delayed]

Ashby | YC 19 | REMOTE | Hiring Engineering Manager (Americas) | $200k–$275k

Ashby is the all-in-one recruiting platform powering hiring at the world's most innovative companies. If you cmd+f "Ashby" you'll see that we're powering many of the job postings in this thread!

We’re looking to scale our engineering leadership team with technical leaders who want to raise the impact of a high-performing organization.

* Not Your Traditional "Jira-Manager": Our EMs are not classic delivery coordinators who shuffle meetings or build heavy processes. Instead, you will own people, hiring bar, technical judgment, and the health of our engineering systems.

* High-Autonomy Team: Because 80%+ of our engineering team is Senior–Staff+ level, our engineers already possess a high degree of ownership. Your focus is less on day-to-day task coordination and more on coaching independent owners, managing ambiguity, and raising team impact.

* Technically Credible Leaders: You will stay close enough to the work to challenge assumptions, review proposals, spot maintainability issues, and jump into the code to debug alongside engineers when needed.

* Organizational Advocates: Beyond your immediate team, you will act as an advocate owning the health and metrics of org-wide areas—ranging from CI/CD health and developer productivity to customer success collaboration and on-call sustainability.

* 100% Remote Async Culture: We maintain an even distribution of engineers across North America and Europe, optimizing for minimal process and maximum focus. * Here's how we're thinking about AI at Ashby:https://www.ashbyhq.com/blog/engineering/ai-ashby-engineerin...

* Full transparency on engineering levels + comp:https://www.ashbyhq.com/blog/engineering/leveling-and-compen...

Stack: TypeScript (frontend & backend), React, GraphQL API, Node.js, Postgres, Redis. (While you won't always be shipping code, you are expected to hold a deep technical understanding of the system).

Full list of open roles:https://www.ashbyhq.com/careers?utm_source=HNwhoshiring

Cambium Assessment Inc | Senior Software Engineer (AI Applications) | Remote (US) | Full-time | No Visa Sponsorship | $140K - $170K | https://www.cambiumassessment.com

Cambium Assessment is a leader in online testing. We build online assessment software systems used by millions of students and thousands of educators.

We're hiring a Senior Software Engineer to own the architecture for AI-enabled software systems. You'll be designing autonomous AI agents with persistent memory, shared state, and multi-step reasoning, embedding them into production EdTech products at scale. This is an IC role where you'll build agentic systems, set up evaluation/safety frameworks, and mentor other engineers.

Tech Stack/Concepts: Python, TypeScript/JavaScript, AWS Bedrock, Tool Calling, RAG, Prompt/Context Engineering.

Requirements: 5+ years of full-stack experience (2+ years at a Senior level); Hands-on experience building agentic systems; Strong Python and TypeScript/JavaScript programming knowledge; Cloud experience (AWS/GCP/Azure).

Note: Due to company policy Cambium Assessment cannot provide visa sponsorship for this role.

Nice to have: Experience with AWS Bedrock, Strands Agents, AI eval frameworks, or an EdTech background.

Apply: https://jobs.cambiumlearning.com/jobs/product-engineering/re...

Fusionbox | Python + TypeScript Engineers | United States | Full-time | REMOTE (US-only)

We're a software engineering consultancy that builds enterprise software the right way. We negotiate the right to open source all our client code, maintain a handful of popular libraries, and our engineers contribute to Django core. We sponsor PyCon, DjangoCon, and Django Girls because we're invested in the ecosystem we build on.

We're looking for software engineers who value software design, system architecture, and collaboration. You should be strong in most of these areas: web application security, relational database design (PostgreSQL query plans, indexes, and constraints, not whatever the ORM emits), Django internals, React, and distributed systems. What you'll actually work on: complex state machines for financial workflows, multi-tenant architectures with row-level security, custom database functions when the ORM isn't enough, and React frontends that handle real-time data without being a mess of useEffect race conditions.

A note on how we work: we think deeply about the systems we build, and we believe understanding comes from doing the work yourself, not from handing it to a model. If you ship code you don't understand, we're genuinely not a fit, and that's fine. If that paragraph made you nod, we want to hear from you.

We're a small team where you'll own features end-to-end (database design to React components) and have opportunities to shape technical decisions. You'll work with a team that practices empathy and values work-life balance. If you've ever wished your job involved more elegant state machines and fewer marketing landing pages, let's talk: info@fusionbox.com.

telli (YC F24) is hiring in Berlin, Germany

https://hi.telli.com/join-us

SerpApi | https://serpapi.com | Junior to Senior Fullstack Engineer multiple positions | Customer Success Engineer | Senior Content Specialist | SEO Specialist | Python/Ruby/PHP/JS/Rust/Kotlin/Swift/Go/PHO Developer Advocate positions | Based in Austin, TX but remote-first structure | Full-time | ONSITE or FULLY REMOTE | $150K - 180K a year 1099 for US or local avg + 20% for outside the US

SerpApi is the leading API to scrape and parse search engine results. We provide 100+ APIs to Google, Google Maps, Google Images, Bing, Baidu, and more.

Our current stack is Ruby, Rails, MongoDB, and React.JS. We are looking for more Junior and Senior FullStack Engineers.

We have an awesome work environment: We are a remote first company (before Covid!). We do continuous integration, continuous deployments, code reviews, code pairings, profit sharing, and most of communication is async via GitHub.

We value super strongly transparency, do open books, have a public roadmap, and contribute to the EFF, and are a Contributing Member of the Rails Foundation.

Apply at: https://serpapi.com/careers

Beautiful.ai | Full-Time | Remote in US & CAN | SaaS B2B Presentation Software | Series B | 16M Funding | AI Industry

1. Account Executive | 140k - 240k USD Base Salary + Uncapped On-Target Commission at 50/50 Split | https://job-boards.greenhouse.io/beautifulai/jobs/4955956007

2. GTM Engineer | $80,000 - $120,000 USD Base Salary | https://job-boards.greenhouse.io/beautifulai/jobs/5055492007

Baton | San Francisco, CA (Hybrid) and Remote | Full-Time

Baton (baton.io) is Ryder's in-house product development group focused on harnessing emerging technologies to redefine transportation and logistics. With $10B in freight under management, our technology reaches every part of the U.S. economy. We design and ship category-defining software that enables Ryder and its 50,000+ customers—including some of the world's most well-known brands—to plan and execute freight intelligently, efficiently, and cost-effectively. Our work includes everything from customer-facing software to the data platform that will power the next era of innovation at Ryder.

Baton's mission: enable supply chain on autopilot.

Ryder acquired Baton in 2022 to power its next wave of digital products. We operate at startup speed, with Fortune 500 reach. If you have a passion for solving complex problems and creating impact for the engine of the American economy, you'll love it here.

Current openings at Baton:

* Group Product Manager, Platform (hybrid, $220,000 - $270,000): https://grnh.se/bd8io8wp7us

* Head of Technical Operations (hybrid, $180,000- $230,000): https://grnh.se/gw86i0tc7us

* Software Engineer - Data Platform (hybrid, $162,000 - $216,000): https://job-boards.greenhouse.io/baton/jobs/5177637007

* Software Engineer - Infrastructure, Data Platform (hybrid, $162,000 - $216,000): https://job-boards.greenhouse.io/baton/jobs/4011484007

* Product Marketing Manager (remote, $90,000 - $140,000): https://grnh.se/r7unwhdx7us

* Product Intelligence & Data Analytics Manager (remote, $90,000 - $140,000): https://grnh.se/lyd76nke7us

* Senior Product Designer (hybrid, $140,000 - $190,000): https://grnh.se/2nlrivyp7us

* Head of IT and Production Support (hybrid, $180,000- $230,000): https://job-boards.greenhouse.io/baton/jobs/5160535007

Aware Health | ONSITE Hybrid 3 days/wk in San Francisco | Full time | https://awarehealth.io

Come build the future of orthopedic care with us! I'm expanding my team again at Aware Health, and I'm hiring a Director of Engineering to help us develop innovative AI agents and AI-powered product solutions in healthcare.

We’re a rapidly growing startup on a mission to deliver high-quality, $0 orthopedic care to people across the U.S.

If you (or someone you know) has expertise in Golang, TypeScript, Python, and a strong desire to build AI in healthcare, please apply or share: https://www.awarehealth.io/careers/dir-of-engineering

Why Aware Health?

→ An MSK product that works — led by our CEO, a world-leading researcher in Direct Access MSK outcomes (NPS: 91+)

→ Real momentum — we’ve more than doubled revenue and covered lives 2 years in a row

→ A small but mighty product team (product, data, engineering, AI)

→ A culture of meritocracy and high-performance (work with smart, driven colleagues)

Mention Hacker News in your application.

Oklo | Remote (US) or Santa Clara or Brooklyn | Full time | https://oklo.com

Join us in pioneering the next generation of nuclear reactors! You'll leverage your software skills alongside nuclear engineers to model, simulate, design, and deploy advanced fission power technology. You will work at the forefront of the nuclear industry, developing novel techniques to reach new levels of safety, efficiency, and resiliency. Come be a part of powering the future with advanced fission power plants to provide clean, reliable, affordable energy.

We are hiring for:

- Software Engineer: https://job-boards.greenhouse.io/oklo/jobs/4018702004

- Senior Software Engineer: https://job-boards.greenhouse.io/oklo/jobs/5739483004

See more opportunities here: https://job-boards.greenhouse.io/oklo

Please mention Hacker News in your cover letter!

Kog (https://kog.ai) | GPU Engineer | Paris, France | REMOTE within a Europe-compatible timezone, one week per month onsite in Paris

We are hiring a GPU Engineer to work on the fastest LLM inference engine on standard datacenter GPUs.

You would own low-level kernel work in CUDA/PTX or HIP/CDNA ISA, the monokernel pipeline, profiling infrastructure inside it, scaling to the frontier MoE models that run in production, and building our own agents that optimize kernels and inference autonomously.

We generate 3,000 tokens/s per request on 8x AMD MI300X and 2,100 on 8x NVIDIA H200, at batch size 1, FP16, no speculative decoding.

At batch size 1, the decode is GEMV, so it is memory bandwidth bound, and MBU is what counts.

We rewrote the whole hot path ourselves, from the assembly on the chip up to the Transformer we designed around it, with the full decode running as a single persistent GPU kernel.

Try it at https://playground.kog.ai

Showing your code is part of the process.

If you are outside a Europe-compatible timezone, relocation to one is required.

Apply: https://jobs.ashbyhq.com/kog/e3950334-a2a6-43cc-a744-df6c386...

Questions, email me at nicolas.constant@kog.ai

Perry Street Software | https://www.perrystreet.com | Remote | Full-Time | Global

Perry Street Software, the largest independent publisher of LGBTQ+ apps globally and creator of SCRUFF (www.scruff.com) and Jack'd (www.jackd.com), is hiring for Senior Ruby Developer.

In this role, you will help build our Ruby API powering our family of mobile dating apps. We are looking for engineers who are passionate about architecture and monads! (Ok just kidding about the last part -- but you can see more about our approach to API development in our Medium blog series at https://medium.com/perry-street-software-engineering, and you can see our contribution to Ruby architecture at https://github.com/perrystreetsoftware/Rubyzen). The position is 40 hours per week and ongoing/full-time.

Interested developers should apply at: https://rubyonremote.com/jobs/73278-senior-ruby-developer-eu...

Applicants should please read this 60-second blog post (https://tombedor.dev/human-attention-and-human-effort/), which we believe applies equally to job applications as it does to generated code.

Purely AI-generated applications will not be considered for this role.

Playit - https://playit.gg Eugene, Oregon. REMOTE okay. USA only.

Looking to hire our first full time engineer besides myself. High impact role, over 100k monthly active users. Cash flow positive.

We run a global network to help people host game servers at home. Most of our backend is in Rust with Postgres DB, website is React SPA in typescript.

Engineering work touches many areas: * low level AF-XDP networking * state synchronization across 20 datacenters * custom ddos mitigation logic * product feature development * front end website dev * front end TUI dev * reliability monitoring and alerting * so much, think creating cloudflare from scratch with focus on gaming and you’re not far off

Send resume over email to apply@playit.gg