Ploid AI | Barcelona, Spain | REMOTE (preferably hybrid) | Core Team | Full-time

We're building an AI-first bioinformatics platform to empower life science researchers with agentic AI and LLMs. Backed by pre-seed funding, a government grant, and customers from biotech, agrotech, and pharma companies, we're looking for a full-stack engineer to join as a core member.

What we're looking for:

• Strong full-stack experience across Go, TypeScript, and Python (Rust is a plus)

• Hands-on AWS infrastructure work (you've built and maintained production cloud environments)

• Experience with multi-tenant architectures: isolation strategies, auth, data partitioning

• Comfort with AI/ML devops: deploying and orchestrating model-serving pipelines, managing GPU workloads, CI/CD for ML systems

• Willingness to own problems end-to-end, from system design to shipping

Nice-to-haves (not all required): LLM integration, RAG systems, HPC infra, cloud/on-prem hybrid systems

About us: We're a team of engineers and scientists with strong academic and industry backgrounds (ex-BCG, PhD in Plant Biotech and Bioinformatics, Mathematics, M.Sc. AI, PhD in Electrical Engineering). We're committed to building something impactful, technical, and genuinely useful for life science.

Apply: hello@ploid.ai

More about us: https://ploid.ai

We also consider internship requests from strong student candidates for research work.

Thanks to everyone who's reached out through previous HN posts, this community has helped us find amazing people.

Foundry Robotics | Founding Engineers | Full-time | Onsite (London, UK)

I'm Gio, CTO of Foundry Robotics. We're an early stage startup building robotics for manufacturing applications.

We are looking for people with one or more of these skills:

1) Tinkerer/mechanical engineer -- Build robots in our lab with a mix of design and hands-on prototyping. Experience with metal fabrication (CAD, CNC milling, 3d printing, sheet metal).

2) Computer vision AI lead -- You will own our vision stack. Experience in object detection and pose estimation, SLAM, FoundationPose, Nvblox etc.

3) Robotics software engineer -- Build our manipulation pipeline. Experience in Nvidia Isaac or similar simulation environments.

Contact: gio@foundryrobotics.co.uk (start subject with "HN:")

(AU ONLY / REMOTE)

Senior engineer to step into a ~30k LOC system (~300 files) and help shape it properly.

Production-style system with real complexity. Interdependent modules, async flows, external integrations.

Stack: Python/FastAPI backend, Next.js frontend, early-stage routing/AI components.

Expectations:

- quickly understand an existing codebase

- trace data flow across modules/services

- identify structural issues and bottlenecks

- make pragmatic improvements without overengineering

Starts with a deep dive and direction, with room to stay involved and build it out.

AU-based only (R&D constraints).

Email: mattahbla+hn@gmail.com

BioLM | Lead Platform Engineer | San Francisco (or Remote) | Full-time | biolm.ai

We're building an AI platform for molecular discovery: think language models for protein and DNA design. Small founding team, moving fast, real ownership.

Looking for a lead platform engineer to own full-stack development across our Console, Builder, and Solutions apps. You'll ship agentic workflows for molecular design, build integrations with sequence/assay ordering providers, and help shape the technical direction of the platform.

Stack: Python, React, Node.js, AWS, Docker, REST/WebSockets. Bonus if you have experience with agentic systems or MCP. Interest in biology/bioinformatics a plus but not required. If you've shipped production systems end-to-end, have strong product instincts, and want to work on something at the intersection of AI and life sciences - we'd love to hear from you.

https://app.dover.com/apply/BioLM/12435b30-67f1-43c2-8c59-6d...

SF or Shenzhen, remote possible for exceptional candidates Hiring FDEs and various Member of Technical Staff roles

Apply here: https://jobs.ashbyhq.com/dimensional

Demos: https://x.com/stash_pomichter

--

Dimensional is the agentic operating system for generalist robotics.

The team is from MIT, CMU, Cornell, DJI, Figure, and has raised $200M+ for previous projects. Backed by the head of Apple Robotics, CEO of HuggingFace, cofounder of GoogleX, CTO of Windsurf, and more.

We launched recently and hit #3 trending on Github. Thousands of developers are now using Dimensional to program physical space.

We’re looking for relentless hackers across Software, Infra, Manipulation, Navigation, and LLM/Agents to join us in SF/Shenzhen to power the next generation of agentive robotics.

Subject: Full Stack Engineer Application - Fatima Usman

Location: Remote (PKT)

Hi,

I’m reaching out regarding your recent post in the HN "Who is Hiring" thread. Stack: React, TypeScript, Node.js, PostgreSQL, Express.js.

What I've shipped:

AI-powered fashion platform (PERN + OpenCV) — Team lead; earned 2nd place at a national competition for a clean, modern UI and complex data processing.

Full-stack music app (React + Node.js + REST API) — Developed during my time at Red Buffer.

15+ Figma-to-React component builds — Expert at translating high-fidelity designs into pixel-perfect, responsive components at PixelSoft Solutions.

Happy to share my GitHub, CV, or jump on a 15-minute call to discuss how I can help scale your platform.

Best,

Fatima Usman fatimaausman8@gmail.com

Pinehurst, TX | Remote, Onsite, Hybrid Senior Systems Architect (Backend / AI-Native / Not a CRUD Role)

Overview We are looking for a senior systems architect, not a feature developer. This role is for someone who: . has designed systems end-to-end . understands how to structure complex backend systems . can work alongside AI-assisted development (not against it) If your primary strength is writing features or following tickets, this is not the role.

What You Will Be Responsible For Evaluating existing systems and identifying what should be: kept, restructured, rebuilt Designing system architecture across: data flow, service boundaries, processing layers Structuring systems that involve: multiple data inputs (APIs, documents, etc.), document ingestion and parsing, asynchronous/background processing Defining backend patterns for: reliability, scalability, maintainability Working in an environment where AI tools (e.g. Claude, OpenAI Codex) are actively used for execution This is a design-first role, not a ticket-driven role.

How to Apply (Required) Please include: . A brief description of a system you personally designed end-to-end . The hardest architectural decision you made in that system . A short explanation of how you currently use AI tools in your workflow Applications without this information will not be considered.

Due to the length of the comments, please visit this doc for full details: https://docs.google.com/document/d/1cCh3gjmq3QYrTKl4qv93QgD1...

Pomelo Care| Remote US (office in NYC or SF)

We’re building a healthier future for women and children. We combine clinical excellence, human connection, and proactive technology to ensure our patients get the care they deserve, from preconception through midlife.

Hiring: Staff Software Engineer, Patient Experience: https://grnh.se/ws5ijibc4us Staff Data Scientist, Growth: https://grnh.se/1tz2tcfw4us

See more opportunities at pomelocare.com/careers

Fullstory | Atlanta, USA & Bogotá, Colombia | https://www.fullstory.com/

Fullstory offers privacy-preserving session replay and analytics for websites and mobile apps. Our session replays are nothing short of magical, and the combination with our automatic analytics creates eye-opening insights.

Atlanta, US engineering roles (semi-onsite, requiring 1 day per week in office):

* Senior Software Engineer, Web Capture - $145~170k + up to 10% bonus - JavaScript/TypeScript, React, Go (golang) - https://www.fullstory.com/careers/jobs/76e583a9-74c0-42d4-ae...

* Senior Software Engineer, Data Pipeline - $160~180k USD + up to 10% bonus - Go (golang), Kubernetes (K8s), GCP - https://www.fullstory.com/careers/jobs/a786962d-68c1-48fa-8b...

Bogotá, Colombia:

* Senior Software Engineer II, Guides & Surveys - $90~93k USD + up to 10% bonus - https://www.fullstory.com/careers/jobs/073bfc41-0ac6-4e59-a5...

We have additional roles for sales, consulting, HR, accounting, and customer support open in Atlanta, London, and some Remote (US) options. See the full list at https://www.fullstory.com/careers?utm_source=092xpqyAkV

For US roles, you can expect regular raises & bonuses, equity, and benefits including: health insurance, 401k matching (Vanguard), annual learning stipend, unlimited PTO, parental leave, and more. I take about 4-5 weeks vacation a year, in addition to ~3 weeks worth of company holidays (federal holidays + the week of Christmas to New Years.)

Folks in other countries can also expect a strong benefits package, but I'm not as versed on the details.

Additionally, you get a 5-week sabbatical after 5 years of employment - I took mine about a year ago, and it was fantastic.

To apply, please submit your info on the website, and our recruiting team will get in touch with you. If you have questions, feel free to reply here or contact me directly. (I'm an engineer on the iOS team, but I'll do my best to answer questions.)

Onos Health | Staff Eng (AI), Lead Eng (Backend), Lead Eng (Data) | San Francisco (Hybrid) | $200-250k + Equity | [https://onoshealth.com](https://onoshealth.com/)

30 cents of every behavioral health dollar in the U.S. is wasted — on ineffective care, administrative overhead, and outright fraud. Onos fixes this by ensuring every healthcare dollar goes toward high quality care.

Our AI platform helps health plans identify where care is going wrong, get members on the right clinical pathway, catch fraud and abuse, and automate reviews that clinical teams currently do by hand. We're well funded by top healthcare investors and live with some of the nation's largest health plans.

Stack: Python/Django, Next.js/TypeScript, PostgreSQL, AWS (Bedrock, ECS, Glue, S3). We ship with Claude Code and CodeRabbitAI.

Hiring:

- Staff Software Engineer (AI) — LLM pipelines for clinical note extraction, level-of-care classification, eval frameworks - Lead Engineer (Backend) — clinical workflow engine, AI/ML pipeline integration, multi-tenant architecture - Lead Engineer (Data/Integrations) — payer data pipelines, EDI X12/FHIR/HL7, claims feed infrastructure

All roles: https://onoshealth.com/career Email: [joinus@onoshealth.com](mailto:joinus@onoshealth.com) (mention HN)

Company: Faqta Location: Utrecht, Netherlands (Hybrid Tue/Thu) Remote: No (NL-based) Type: Full-time Salary: €3858–€4244/month + 8% holiday pay

Medior Backend Developer (Node.js / TypeScript)

Faqta builds a platform used by thousands of teachers across the Netherlands to manage lessons and track student progress.

We’re modernizing our backend toward a more scalable, modular architecture.

You’ll work on systems that process student results and support classroom workflows at scale.

Tech stack: Node.js, TypeScript, Express MySQL, Redis, BigQuery GCP, Kubernetes

Small team, high ownership. Engineers work end-to-end from design to deployment.

Apply: https://vacatures.faqta.nl/vacature-medior-backend-developer

Art Tech Startup (stealth) | Technical Co-Founder | Remote or NYC | Equity

I'm building an art tech startup, and I am seeking a highly driven full-stack technical co-founder ideally located in NYC. You should ideally have a proven track record of launching and operating tech products that successfully generated sales or a substantial user base in the US or Western Europe.

I am a finance, strategy and tech professional with experience co-founding a dating website that secured paying users in its first month of launch. I handled all non-technical work, including go-to-market, partnerships, strategy, UI/UX design, and marketing. Professionally, I've advised tech executives and founders at early-stage to global enterprises. I know how to build and scale tech products from 0 to 1.

Reach out to learn more: https://www.linkedin.com/in/fai833/

Hey HN! I'm hiring aggressively to scale our team at Airspace Intelligence (https://www.airspace-intelligence.com)

Series B, onsite in Boston (all levels) and Seattle (Senior+).

We're building the software layer for airspace and critical infrastructure operations. Think real-time optimization across thousands of flights, grid assets, and logistics networks — the kind of problem where your state space is enormous, constraints shift constantly, and the humans in the loop are making life-safety decisions on tooling that hasn't meaningfully improved in decades.

We're hiring across Product, Infrastructure, and ML. If you're a performance minded front-end (web) engineer - I particularly would love to hear from you.

Here's one of our roles https://www.airspace-intelligence.com/careers/role?=6462d3d1... - there's a puzzle at the bottom that'll be trivial for this crowd, but it'll get you my email directly. If you go that route, drop "HackerNews" in the subject so I can prioritize you.

If building software for critical systems sounds interesting, I'd love to hear from you.

Hey all, Cassidy (https://cassidyai.com, Series A, ONSITE: New York City) is growing fast and we're hiring across a few critical roles in NYC.

Senior & Mid-level Software Engineers - end-to-end product engineering and helping build systems that scale

Technical Chief of Staff - CTO's operational right hand. Picks up hard, ambiguous problems across engineering, compliance, and commercial conversations and owns them end to end.

Cassidy is an AI agent and automation platform for non-technical knowledge workers. By connecting to a company's knowledge where it lives and building intuitive core primitives, Cassidy lets non-technical teams automate large swaths of busy work, freeing them up to do the work that really matters. Series A, 25 people, growing fast.

GTM Engineer | TestGorilla

TYPE: Full-time

LOCATION: Remote - Spain, UK via EOR, the rest between UTC +2 to UTC +5:30 in our hiring countries via contract (https://testgorilla-1680540968.teamtailor.com/pages/hiring-a...)

REMOTE: Yes (async-first)

VISA: No

DESCRIPTION: TestGorilla is hiring a GTM Engineer to build and scale an AI-enabled GTM system across Sales, Marketing, and Customer Success.

This is not a traditional RevOps or Analytics role. You’ll design and implement workflows, automations, and integrations that make GTM strategy execute reliably at scale.

Build & maintain GTM workflows (HubSpot, Gong, integrations) Automate routing, alerts, deal rules, and inspections Translate revenue strategy into system logic Connect product, sales, and customer data Enable AI-driven GTM signals (e.g. deal risk, expansion) Reduce manual ops work through automation

You should have experience with GTM/RevOps systems and be comfortable working with APIs, integrations, and data flows. Systems thinking and ability to work from ambiguity are key. Interest in AI-driven workflows is a plus.

COMPENSATION: €54,840–€68,550 + SARs (equity)

JD: https://testgorilla-1680540968.teamtailor.com/jobs/7143357-g...

CONTACT: talent@testgorilla.com

Rust engineer Polars

TYPE: full-time

LOCATION: Amsterdam

REMOTE: Optional, Based in the Netherlands is preferred

VISA: No

DESCRIPTION: Polars is the company founded from the Polars OSS project. The company is building a distributed query engine and managed data platform that can run the full polars API with different scaling strategies. (Almost) Our whole tech stack is in Rust and we are building the platform from scratch.

    Rust Software Engineer - Performance: https://hiring.pola.rs/o/performance
    Rust Software Engineer - Query Engines: https://hiring.pola.rs/o/query-engine

CONTACT: hr@polars.tech

Senior Python Backend Engineer | REMOTE

We’re looking for Python backend engineers to work on a trustless supercluster of performance-proofed GPU-enabled sandboxed docker container runners controlled by truly decentralized algorithms (not just PAXOS or RAFT).

Wow, that was a mouthful...

If you found it interesting, join Reef Technologies and tackle complex technical challenges like this on your own terms:

Contribute from wherever you like—we are fully remote Set your own time commitment, as long as it’s at least 30h per week See how we work in our handbook: github.com/reef-technologies/handbook Influence the way we operate through our Sociocracy 3.0 decision-making process

Salary on a B2B contract:

45-70 USD or 180-280 PLN per hour Flexible work schedule (as measured with a time tracker) We automatically adjust rates based on inflation twice a year

We're looking for someone with 5+ years of programming experience, including at least a year with Python (including opensource and significant personal projects).

So, what do you think? You don't even need a CV; just go to https://careers.reef.pl/?utm_source=hackernews and shoot a few quick commands to apply.

Contact: hiring@reef.pl Web: https://reef-technologies.com/

Quick heads-up! Please list the location (REMOTE / REMOTE US / ONSITE), post only if you’re hiring for your company, and keep it to one post per company. If your company isn’t well-known, add a short description. Commenters, stay on-topic, and readers, only reach out if you’re genuinely interested.

Post Up| Full time | Senior Backend Engineer | Vancouver, BC (Hybrid) | Salary: $120-$130k CAD | https://www.postup.pro

We're building the Databricks for content production, starting with post. Our orchestration engine coordinates pipelines end to end and turns post-production workflows into a persistent graph of assets and transformations, which are deterministic, verifiable, and nearly instant at scale, powered by a high-performance compute layer. We're building this AI-native from the ground up; ML inference is embedded throughout the pipeline, not bolted on.

Stack: On-prem, HPC clusters, distributed storage systems, GPU pipelines, real-time video compute.

We're looking for our founding senior backend engineer who wants to work on genuinely challenging infrastructure problems across distributed systems and media processing with immense scale. Should be familiar with Golang, Postgres, Distributed systems, Distributed filesystems (e.g. HDFS, Ceph, etc). If that sounds interesting, reach out directly to me at wilson@postup.pro.

Me: https://www.linkedin.com/in/hayswilson/

How to apply: Email me directly at wilson@postup.pro or Submit here - https://www.notion.so/Founding-Senior-Backend-Engineer-31031...

Atomic Tessellator | Lead Front-end Engineer | Full time, remote (UTC+12) | https://atomictessellator.com

Atomic Tessellator is the computational infrastructure for advanced materials, enabling defence and aerospace organisations to rapidly model, test, and optimise materials under extreme constraints. Our mission is to remove the materials bottleneck so civilisation can advance at the speed of computation.

We're hiring for an experienced Lead Front-end engineer to take ownership of our platform. Ideally you should be within +- 4 hours of UTC+12, unless very senior. Apply here: https://atomictessellator.com/careers/front-end-engineer