Fusionbox | Python + TypeScript Engineers | United States| Full-time | REMOTE (Legal to work in the US)

We're a software engineering consultancy that builds enterprise software the right way. We negotiate the right to open source all our client code, maintain a handful of popular libraries, and our engineers contribute to Django core. We sponsor PyCon, DjangoCon, and Django Girls because we're invested in the ecosystem we build on.

We're looking for software engineers who value software design, system architecture, and collaboration. You should be comfortable with about half of these areas and eager to learn the rest: web application security, relational database design (PostgreSQL, beyond "SELECT *..."), Django internals, React, and distributed systems. What you'll actually work on: complex state machines for financial workflows, multi-tenant architectures with row-level security, custom database functions when the ORM isn't enough, and React frontends that handle real-time data without being a mess of useEffect hooks.

We're a small team where you'll own features end-to-end (database design to React components) and have opportunities to shape technical decisions. You'll get paid to write source code with a team that practices empathy and values work-life balance. If you've ever wished your job involved more elegant state machines and fewer marketing landing pages, let's talk: info@fusionbox.com.

MiLaboratories | Bilbao, Spain | ONSITE | VISA SPONSORSHIP | RELOCATION SUPPORT

We are MiLaboratories, the team behind Platforma.bio & MiXCR. We are building the "OS for Biology"—a platform that processes terabytes of genomic data to accelerate biological discovery and drug development.

We are a deep-tech research lab, not a typical SaaS. We work fully on-site in Bilbao because the complexity of our problems (high-performance computing + biological nuances) requires high-bandwidth, in-person collaboration.

We are hiring for three core roles:

1. Senior TypeScript Engineer (Desktop Platform / SDK): This is not a dashboard or a simple web GUI. You will build the architecture of our Desktop Platform—a high-performance local application that acts as the "OS" interface. You will deal with complex state management, massive data throughput, and bridge directly with our high-performance Rust data layer. We need someone who treats the browser engine as a runtime for heavy applications, not just for websites.

2. Senior Go Engineer: You will build distributed systems for high-load genomic data processing. This is not CRUD. We need someone who understands memory management, concurrency, and algorithmic efficiency at scale.

3. Bioinformatics Developer (Antibody Discovery): You will work on the scientific core, developing production blocks for NGS data analysis and antibody structure prediction. You should be fluent in both code and biology (Builder profile, not just analyst).

The Offer:

Comp: Top-tier EU salaries (~€90k - €120k).

Tax Advantage: Bizkaia has independent tax autonomy. You qualify for the "Special Impatriate Regime" (30% salary tax exemption + expense deductions).

The Reality: Your effective tax rate drops to ~15-20%, yielding a significantly higher net income than London or Berlin.

Stock: We grant ESOP and treat equity as a life-changing wealth vehicle, not a "nice to have."

Relocation: Comprehensive "Soft Landing" package (Visa, temporary housing, school search).

Location: Bilbao is a hidden gem—ocean, mountains, and high quality of life with a low cost of living.

Process: No HR screening. You will talk directly to the engineering team.

Email me (I am the CEO): stanp@milaboratories.com. Please mention "HN" in the subject and include your GitHub.

Puma.tech | Remote-first with PST overlap | iOS/MacOS, Android, Ai/ML, Growth | https://puma.tech

Hi all, I’m Yuriy, founder of Puma.tech. Previously worked as software engineer & developer advocate at Cloudant (YC S08, Acq. by IBM), Meteor (YC S11), Parse (YC S11, Facebook/Meta), and explored AI/ML (computer vision for self-driving cars).

We have two products:

1. Puma Browser (iOS & Android) – browser with built in LLMs & Wallets. Private by design.

2. PumaAI app for Mac – ChatGPT/Atlas, but with ability to pick different model providers and fall-back to local-first ones for data privacy.

Open Roles: Eng (iOS/MacOS, Android, Ai/ML, Browser Extensions), Based Social Media Intern; Internships: Eng, Design, Growth

We’ve raised a few rounds from some of the best builders in crypto and ai:

Protocol Labs (YC S14), Chris Larsen (Ripple), Anatoly Yakovenko (Solana), Illia Polosukhin (NEAR Protocol), Sridhar Ramaswamy (Snowflake CEO, Neeva, Greylock), Jason Warner (poolside.ai, ex-GitHub CTO), Don Ho (Orange DAO, Quantstamp W18), Evil Rabbit (Vercel), John Phamous (SF Compute) and other amazing builders.

How to Apply: email careers+hn [at] puma.tech with your GitHub, a note on what you're most proud of building and what you'd like to build next.

Thank you!

Hike Medical | Boston (ONSITE) | Senior+ Software Engineer

Hike Medical is reinventing musculoskeletal care, starting with feet. Our proprietary AI-vision platform turns a 30 second web based (yes, no sensors) foot scan into precision engineered, 3D-printed insoles that prevent pain before it starts. We're already protecting on-their-feet workforces at Fortune 50 leaders, major health systems, and middle America manufacturers. Fresh off a stealthy round with top tier VCs, we run a fast, no BS, execution first culture out of Boston’s Seaport as we sprint toward $100M ARR and standing with 10M Americans as they step into their shoes daily.

As a Senior Software Engineer, you’ll build and ship the core systems behind Hike’s AI healthcare platform. As the backbone of Hike's high-growth, mission-driven platform, you’ll design scalable services, implement production AI, and deliver user experiences that improve patient outcomes. From day one, you’ll have real autonomy and clear impact on transforming the US healthcare system.

What You'll Work On:

* Architect, build, and optimize high-performance, scalable systems that power AI-driven solutions.

* Design resilient, serverless architectures in a TypeScript and AWS environment.

* Develop developer-friendly APIs and SDKs that enable seamless integration across platforms.

* Build and refine high-speed data processing pipelines that drive clinical-grade AI insights.

Ideal Candidate Profile:

Technical Skills

* AWS & TypeScript Expert – Comfortable making infrastructure decisions, optimizing cloud deployments, and managing scalable architectures.

* Experience designing, building, and maintaining backend systems that power real-time, AI-driven applications.

* Strong experience in building and optimizing developer-facing SDKs and APIs. Skilled in real-time data processing pipelines and optimizing system performance at scale.

* A thoughtful approach to building secure, resilient, and fault-tolerant systems.

Helpful Characteristics

* Product-Minded Engineer – You think about how your work impacts real users.

* Strong Communicator – You clearly explain your ideas, challenge assumptions, and collaborate across engineering, AI, and product teams.

* Thrives in Collaboration – You push back, ask tough questions, and elevate the team.

* Driven to Ship – You want full control over your work, from architecture to deployment, and you’re eager to move fast.

* Mission-Focused – You’re not here to optimize ad clicks. You want to build technology that changes lives.

$150K – $225K • Offers Equity • $15k relocation bonus (if necessary)

Apply: https://jobs.ashbyhq.com/hike-medical/c5a39cb5-fdaa-457d-86d...

Level 12 | Full Stack Web Developer - Python, JavaScript, SQL | Mid-Level & Senior | REMOTE | SALARY:$95K-145K+ | https://www.level12.io/careers/

Level 12 is a software consulting and custom development agency. We have mid and senior level positions. Our job descriptions are written by developers for developers. No HR fluff here, we want you to know what you are really getting into:

https://www.level12.io/careers/

- We have a commitment to transparency and offer a "no surprises experience" throughout the interview and hiring process. We value candor...as evidenced by the length of our job description. :)

- Our CEO prefers the title CED, Chief Executive Developer. Engineering and operational concerns don't take a back seat when potential sales come to the front door.

- You will be working remote with a team that is all working remote and has been for years. Let's make the best use of our time by not commuting.

- We practice and preach sound development practices. You are likely to learn and grow as a developer while working here.

- You are committed to automated testing of all the software you write (our apps typically have 92%+ test coverage).

- We have a no-drama office policy. We value and cultivate enjoyable working relationships among team members. No jerks allowed!

- We emphasize work/life balance and adopt policies that make sure our people don't get burnt out. For instance, our PTO/Vacation policies are designed so that you actually use them.

- If you apply, we guarantee that we will give you a response, whether "yay" or "nay". No black holes here!

NOTE: our intent to hire is currently tentative but should be resolved one way or the other in the next couple weeks. So, if you are interested, read the job description but, for now, don't go through the entire application process unless you really want to. Just email me (the CEO) with a clean dad joke, or your take on Kirk vs Picard, and reference your interest: randy.syring@level12.io. I'll follow-up in a couple weeks when I know for sure if we are going to be taking applications.

Adobe - Brand Concierge | 2 Sr. AI Systems Architect with ML | San Jose, CA | ONSITE (3 days - hybrid) | Full-time Turn conversations into conversions. learn more https://business.adobe.com/products/brand-concierge.html

We started around 8 months ago, have 80k+ beta users, and have been Product Hunt’s Product of the Day twice. Seed-stage (oversubscribed, will be announced soon) with meaningful equity for every role.

We’re hiring 2 Architects, Start up culture, build fast, ship fast

APPLY NOW at https://careers.adobe.com/us/en/job/ADOBUSR158280EXTERNALENU... send me a message on LinkedIn , be creative :) https://www.linkedin.com/in/emilthomasca/

ELDRICK.com | Austin, TX / Remote | Hiring Founding AI Engineer + Videographer

ELDRICK is the world’s #1 AI golf club fitter, trained on 80,000 real club fittings. We’re building an AI-powered golf fitting platform using real data to replace guesswork and brand bias.

OPEN ROLES:

FOUNDING AI ENGINEER (GENERALIST) Austin, TX preferred | REMOTE (strong candidates) Comp: $200k+ base + equity

Founding-level role working directly with founders on core AI systems. Build end-to-end AI translating golfer inputs, swing data, and fitting history into equipment recommendations. Looking for strong applied AI/ML or LLM experience, generalist mindset, product instincts. Must be a golfer — include your handicap in the email.

VIDEOGRAPHER / SHORT-FORM CONTENT CREATOR Fort Wayne, IN | ONSITE Comp: $50k–$75k base

Shoot and edit short-form video (TikTok/Reels/Shorts). CapCut required. Familiar with AI tools like Midjourney or Kling. Junior-to-mid level. Golf interest a plus.

Apply: hi@eldrick.golf

Sphinx Defense | Software Engineering | Remote (US Only) | https://www.sphinxdefense.com

Sphinx Defense builds software to solve complex national security problems for America and its allies. Founded by engineers and technologists with deep experience across commercial and defense technology, we're building a vehicle-agnostic communication infrastructure to enable satellite operators to securely utilize antenna networks and maneuver satellites in real-time. We're bootstrapped, profitable, and growing aggressively.

To learn more about who we are, our engineering culture, and whether this is the right place for you, https://sphinxdefense.com/

Our current openings are: Sr. Software Engineer - Frontend - Colorado Springs : https://grnh.se/hj59fohy8us

Don’t see a role that aligns with your interests or don’t have the specific Space/ Command & Control experience? Apply to the general interest application and list what type of role you would be interested in : https://grnh.se/4ce199d68us

Check out our open roles: https://sphinxdefense.com/careers/#open-positions

Neo.Tax | Senior Full-Stack Engineer | Remote (US Timezones) | Full-time

Neo.Tax is automating enterprise accounting and tax with AI. We help companies like Notion, Mercury, Brex, and Whoop calculate R&D tax credits and capitalize software costs in hours instead of weeks—saving millions in manual consulting fees. Our stack is TypeScript/Node.js/React/SQL with distributed data pipelines processing millions of records from Jira, GitHub, payroll systems, and accounting software.

We're hiring a Senior Full-Stack Engineer to join our 7-person engineering team. You'll build our software capitalization product end-to-end—designing data ingestion pipelines, modeling flexible schemas for diverse customers, building integrations with third-party APIs, and shipping customer-facing features that finance teams use monthly.

What we're looking for:

- 7+ years full-stack experience with TypeScript, Node.js, React, SQL, and distributed systems - Ownership mentality—you can take product requirements and break them into iterative deliverables that ship value quickly - Comfortable with ambiguity and greenfield problems - Strong fundamentals (we use AI as a multiplier, not a substitute for engineering skills)

*Why join now*: We're preparing for Series B with 2x YoY growth, multiple profitable months, and real product-market fit. You'd be joining at a stage where early employees have outsized impact on trajectory.

Salary: $190k–$210k + equity. Remote-first, but we prefer timezones that overlap with Mountain View, CA.

Apply: https://apply.workable.com/neo-tax/j/BD05B5C7B1/

Staff / Principal Product, Backend, Distributed Systems Engineers - Artemis — NYC

Hiring 7+ yr Staff/Principal engineers to own exabyte ingestion, streaming/federated analytics, and AI-native detection (product + infra) at our Stealth AI-security startup (seed $15M).

Stack: Python/Node/Rust, React/TS, Kafka, ClickHouse, AWS.

Ship end-to-end: design → prod → detection stories that customers use daily.

Prefer experience at scale (Google/Meta/AWS/Abnormal/Wiz) - we have a super experienced technical team.

Email christina@goartemis.ai + with CV + one line on what you’d own - I’ll reply personally.

ToucanTix | Lead Engineer | Berlin/REMOTE (EU) | Rails | €60k-€90k

We're the ticketing platform behind major theme parks, zoos, and experience villages across Germany and the USA. Spin-off from COMBASE AG focusing on leisure/culture.

The situation: 2-engineer team building on COMBASE's platform. We handle online ticketing, visitor management, capacity control. CSO just joined from major competitor, closing enterprise deals. We're staying lean using AI tools to compete with larger competitors.

Technical challenges: - Multi-tenant booking with venue-specific business logic (pricing rules, capacity, timed entry) - Real-time capacity management across access zones - Integration with COMBASE platform - Making AI-augmented development work in production

The role: Lead engineer working with founder. Own features E2E, architecture decisions, full-stack but backend-heavy.

You fit if: - 3+ years shipping production code - Excited by small teams doing more with AI - Prefer ownership over structure - Rails or quick to learn

Stack: Rails, Svelte, PostgreSQL, GraphQL, GCP

Perks: Remote (occasional Berlin meetups), MacBook + home office, free attraction admission, stable backing (COMBASE: 80+ people, 3 decades)

Apply: jobs@toucantix.com Include: CV/LinkedIn, a technical challenge you're proud of, why this interests you, favorite attraction. in subject.

https://www.toucantix.com/careers/lead-engineer

[delayed]

SEEKING GROWTH PARTNER | Growth | ActorDo Not a job, but can be one. Exploring alignment.

I’m building ActorDo, an AI work assistant that actually helps people get work done. Email, calendar, tasks, context. Product is live. Users are using it.

Now I’m looking for a growth partner, not a tactic executor. With experience on US market.

This is about: - positioning and narrative - real distribution wedges - fast experiments and feedback loops

Close to product. Close to users. No fluff.

Looking for a self-driven growth marketer who likes early-stage chaos, thinks in systems, and wants real ownership.

If this clicks, let’s talk. Must provide references.

ActorDo info: https://actordo.com

Flotive AI | https://flotive.ai | Founding Software Engineer | Jersey City / New York Metropolitan Area / NYC Area | Onsite (Hybrid OK)

Flotive is building an AI-powered platform to reshape the grid. We help energy developers identify buildable sites and manage regulatory complexity so power generation and large loads (such as data centers and manufacturing facilities) can come online faster.

Salary: $150-180k + equity

Details here: https://flotive.notion.site/founding-software-engineer

Midpage | https://midpage.ai | Senior Software/Data Engineer | prefer NYC, open to remote | Full-time | $170-240k + equity

Midpage is seeking a senior engineer to help us catalog the world's legal data. Our dataset currently covers US case law and powers some of the largest law firms, legal technology platforms, and AI companies through our webapp, API, MCP, and custom data services. We're currently the only vendor openly widely selling this data in the US and customers appreciate that we have good citation linkages and a citator (indication of which judgments have been overruled/criticized).

We're looking to expand data coverage, adapt our infrastructure to our scaling enterprise needs, and find new ways to enrich our data offerings and delight our developer customers.

We're a team of 7, mostly in-office in lower Manhattan with a few remote/international teammates. Seeking a backend generalist with deep Python + Postgres experience who's ready to move quickly. Prefer NYC but flexible.

If interested email ben/dot/hoffner/dash/brodsky/at/midpage/dot/ai with HN in the subject.

Jurata | Software Engineer (Frontend/Fullstack) | Zurich, Switzerland | ONSITE | Full-time Jurata is a LegalTech startup building an online one-stop shop for legal, accounting, and tax services. We help thousands of SMEs get fast, affordable access to professional support. Heavy focus on automation and AI. We're looking for versatile engineers who thrive in a TypeScript environment and enjoy owning features end-to-end. What you'll do:

Build and maintain Next.js frontends Migrate legacy apps from no-code tools (WeWeb/Retool) Deliver fullstack features (backend: Nest.js, Python) Own problems from idea through release and monitoring

Stack: TypeScript, Next.js, Nest.js, Python, MongoDB, Vercel, AWS Looking for:

TypeScript and Next.js experience Strong eye for design (you can build beautiful UIs without a Figma file) You actively use AI coding tools (Cursor, Windsurf, etc.) Builder mindset, comfortable working autonomously

Benefits: 25 vacation days, ESOP, free gym membership, team lunches, central Zurich office with snacks and drinks. EU/EFTA citizenship required (or willingness to relocate to Zurich). Apply: https://join.com/companies/jurata/15604453-fullstack-softwar... (mention HN)

MixMode.ai | Sr. Software Reliability Engineer | Remote | Fulltime

https://job-boards.greenhouse.io/mixmode/jobs/5011774007

Mozart AI | 2 Full-Stack Engineers (FE-leaning + BE-leaning) | London, UK | ONSITE (central London) / Hybrid | Full-time

Mozart AI is a Digital Audio Workstation (DAW) with built-in AI Co-Production. We empower what we call the ‘Hybrid Musician’, an artist driven by human creativity and assisted by AI. You could say we want people to become “vibe musicians”.

We started around 8 months ago, have 80k+ beta users, and have been Product Hunt’s Product of the Day twice. Seed-stage (oversubscribed, will be announced soon) with meaningful equity for every role.

We’re hiring 2 engineers:

Full-Stack Engineer (Frontend-leaning): product UI/UX, React, Zustand, realtime-ish creative workflows, making the browser feel like a native studio

Full-Stack Engineer (Backend-leaning): platform + APIs + data and db design, reliability + performance, supporting fast product iteration

What you’ll like here:

Small team, high ownership, ship fast (by choice, you feel the urgency to change music creation)

Working on generative audio + creative tooling (hard but really fun problems)

More about us (Forbes): https://www.forbes.com/sites/charliefink/2025/07/01/mozart-a...

Try Mozart AI: https://mozartai.com/

Apply, we (I) review every application: send me an email at pascual@arthos.inc , be creative :)

Nomi.ai | https://nomi.ai | Senior Machine Learning Engineer | Remote (Global) | Full-time | $150k–$250k + equity

At Nomi, we're building AI companions that form deeply meaningful, humanlike relationships and immersive roleplaying experiences. With over a million users growing at ~8% month-over-month, your work directly impacts millions of lives. Our users tell us we've helped them find self-worth, leave unhealthy relationships, try therapy, and even save their lives. See countless real user testimonials here: https://nomi.ai/spotlight/ and our recent news coverage here https://www.cnbc.com/2025/08/01/human-ai-relationships-love-...

As an ML Engineer or Senior ML Engineer, you'll lead innovation in large language model (LLM) post-training, retrieval augmented generation (RAG), and agentic capabilities, directly shaping how users connect with our AI.

We offer:

    * Full autonomy to experiment and deploy cutting-edge ML techniques
    * A fully remote, async culture emphasizing results over meetings
    * International team with visa sponsorship available
    * For US employees: 401k (100% match up to 5%), fully covered health insurance, equity

    * Extensive hands on experience with things such as multinode training, rlhf, knowledge distillation, test time compute, rag, realtime video
    * Up to date with SOTA in LLM post training (would love to hear what research paper you think is or would be most impactful for our roadmap!)
    * Genuine passion for our product, finds the idea of engaging with our community on Discord/Reddit to be a pro (it is a very different experience than developing enterprise software!)
    * A high internal bar for excellence and relentless drive

Mason | Software Engineer | Fulltime | San Francisco | thisismason.com

We're building an agent to manage single family rental properties across the United States. We currently manage ~4,000 homes, are growing quickly, and are looking for full stack, back-end leaning engineers who would love to contribute to a state of the art agent.

I've written a bit about our culture + product before:

-> What it means to be "in-person" with our customers: https://medium.com/@maspinwall22/being-there-5c167dd8b163 -> LLM Communications in the wild: https://medium.com/@maspinwall22/llm-communications-in-the-w...

If interested, reach out directly to me: michael@thisismason.com